三甲基氯化锡中毒并发心律失常临床分析  

Clinical analysis of trimethyltin chloride poisoning cases complicated with arrhythmia

作　　者：袁经林[1] 杨晨[1] 赖平[1] 邱悦群[2] Qiu Yue-qun;Yuan Jing-lin;Yang Chen;Lai Ping(Department of Cardiovascular,The First Affiliated Hospital of Gannan Medical University, Ganzhou,Jiangxi,341000,China;Gannan Medical University,Ganzhou, Jiangxi,341000,China)

机构地区：[1]赣南医学院,江西赣州341000 [2]赣南医学院第一附属医院心脏医疗部,江西赣州341000

出　　处：《当代医学》2017年第17期7-9,共3页Contemporary Medicine

基　　金：江西省教育厅科学技术研究项目(GJJ160987)

摘　　要：目的探讨三甲基氯化锡中毒并发心律失常的发病机制及其临床意义。方法对387例三甲基氯化锡中毒并发心律失常患者心电图相关资料进行回顾性分析。结果三甲基氯化锡中毒并发心律失常发生率为41.9%,严重中毒患者易并发心律失常,与患者中毒途径、时间有一定关联。患者可有不同程度的出现心律失常,主要表现为窦性心动过速、窦性心动过缓、室性早搏、ST-T改变等。结论三甲基氯化锡致心律失常可能与低钾、窦房结及心肌异位兴奋性增高或中毒性心肌炎有关,其发生机制值得进一步研究。Objective To investigate the pathogenesis and clinical significance of the poisoning cases induced by trimethyltin chloride complicatedwith arrhythmia.Methods The electrocardiograms of387poisoning cases induced by trimethyltin chloride complicated with arrhythmia were reviewed.Results The incidence rates of arrhythmia induced by trimethyltin chloride poisoning was41.9%,the severe poisoning cases wereinclined to complicate with arrhythmia.It is related to the ways and times of poisoning.the poisoning cases induced by trimethyltin chloride couldhave different degrees of arrhythmia,mainly for sinus tachycardia,sinus bradycardia,ventricular premature beat,ST-T change etc.Conclusion Arrhythmiainduced by trimethyltin chloride poisoning may be associated with low potassium,the excitability of the sinoatrial node and myocardial ectopicincreased or toxic myocarditis,the mechanism is worthy to further study.

关 键 词：三甲基氯化锡 中毒 心律失常 心电图 

分 类 号：R541.7[医药卫生—心血管疾病] R595[医药卫生—内科学]