人工真皮在头皮恶性肿瘤颅骨外露创面修复中的应用  

The Application of Artificial Dermis in the Repair of Skull Exposure by Scalp Malignant Tumor

作　　者：李虎[1] 史高峰[1] 蒋朝龙[1] 钱心炜[1] 高凤山[1] LI Hu;SHI Gao-feng;JIANG Zhao-long;QIAN Xin-wei;GAO Feng-shan(Department of Plastic Surgery,Affiliated Hoapital,Jiangnan University,Wuxi 214000,Jiangsu,China)

机构地区：[1]江南大学附属医院(无锡市第四人民医院)整形外科,江苏无锡214000

出　　处：《中国美容医学》2017年第6期32-34,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨人工真皮(皮耐克)在修复头皮恶性肿瘤颅骨外露创面中的临床应用。方法:选择2014年1月至2016年5月于本院行头部恶性肿瘤治疗的患者30例,术中按无瘤原则切除后颅骨外露,于颅骨外板均匀分布、间隔1.0cm钻孔至板障层,至新鲜出血,人工真皮(皮耐克)覆盖创面,待2~4周后人工真皮与创面结合生长良好,于人工真皮(皮耐克)表面行自体刃厚皮植皮。结果:30例患者移植刃厚皮片存活率100%,生长良好;3个月后随访愈合良好,皮肤弹性好,无局部皮肤破溃、肿瘤复发等。结论:人工真皮(皮耐克)在无血供颅骨表面能形成类似人真皮的组织结构,从而为创面修复提供可靠的支撑,是一种快速、简单、有效处理头皮恶性肿瘤颅骨外露的方法。Objective To investigate the effect of artificial dermis(Pelnac)in the repair of skull exposure by scalp malignant tumor.Methods From January2014to May2016,30patients with malignant tumors of head,postoperative pathology confirmed forcancer.intraoperative,according to the principle of tumor-free after resection of skull exposure in patients,in cranial uniformdistribution,interval1.0cm drilling to the diploic layer,to fresh hemorrhage.Artificial dermis(Pelnac)covered the wound,after2-4weeks of artificial dermis and wound healing well,and do the skin-grafting with the autologous split-thickness skin.ResultsAll the30patients’split-thickness skins survived well.Follow-up3months,all the patients healing well,with good skin elasticity,no local skin ulceration,without tumor recurrence and so on.Conclusion The artificial dermis(Pelnac)can form the a structuresimilar to human dermis above the surface of non-blood supply skull,which can provide reliable support for wound repairing.It’sa rapid,simply and effective way to dealing with the skull exposure by scalp malignant tumor

关 键 词：人工真皮 皮耐克 头皮恶性肿瘤 颅骨外露 

分 类 号：R622[医药卫生—整形外科]