抗病理性瘢痕中药单体的应用研究进展  

Advance in Components of Traditional Chinese Medicine in Treatment of Pathological Scar

作　　者：孙燕 连娜琦 李泰平[2] SUN Yan;LIAN Na-qi;LI Tai-ping(Pharmacy of Nanjing Meishan Hospital, Nanjing 210039,Jiangsu China;Pharmacy of Nanjing Medical University Friendship Plastic Surgery Hospital, Jiangsu Nanjing 210029, Jiangsu China)

机构地区：[1]南京梅山医院药剂科,江苏南京210039 [2]南京医科大学友谊整形外科医院药剂科,江苏南京210029

出　　处：《中国美容医学》2017年第6期133-136,共4页Chinese Journal of Aesthetic Medicine

基　　金：南京医科大学科技发展基金重点项目(2014NJMUZD040)

摘　　要：瘢痕是创伤愈合过程中一种正常的生理反应,但过度修复导致病理性瘢痕的形成,从而会影响皮肤美观及造成功能障碍,影响患者的身心健康。由于病理性瘢痕形成机制尚未完全明确,目前依然缺乏有效的防治方法。近几年,中药单体防治病理性瘢痕的实验研究逐渐增多。本文拟就目前常用于抗病理性瘢痕的中药单体及其作用机制作一综述,为中药单体治疗瘢痕研究提供参考。Scarring is a naturally physiological response in the process of wound healing and tissue repair;however,excessiverepairs lead to the formation of the pathological scar,which affects the appearance and functions of the skin,further affectingpatient’s physical and mental health.The exact pathophysiology of pathological scar formation remains unclear.The effectivemethod for prevention and treatment is still not available.More and more studies have focused on the treatment of pathologicalscar involving various monomers of Traditional Chinese Medicine(TCM).This review aims to summarize the pharmaceuticalfunctions of common monomers and the mechanism underlying anti-pathological scarring,in order to provide a reference forthe study of TCM treatment of scar.

关 键 词：病理性瘢痕 增生性瘢痕 瘢痕疙瘩 作用机制 中药单体 综述 

分 类 号：R619.6[医药卫生—外科学]