急性重症有机磷农药中毒患者60例预后临床因素分析  

Clinical factors analysis of prognosis of 60 patients with acute severe organophosphorus pesticide poisoning

作　　者：李旎[1] 李晶[1] 周定耕[1] 王彪[1] Li Ni;Li Jing;Zhou Dinggeng;Wang Biao(Emergency Department,the Second Hospital Affiliated to Nanhua University(Hengyang City,Hunan Province)421001)

机构地区：[1]南华大学附属第二医院急诊科(湖南衡阳),421001

出　　处：《中国社区医师》2017年第19期74-75,共2页Chinese Community Doctors

基　　金：湖南省卫生厅科研基金(B2014-054)~~

摘　　要：目的:探讨影响急性重症有机磷农药中毒患者预后的相关临床因素。方法:收治急性重症有机磷农药中毒患者60例,比较死亡组和生存组的临床资料。结果:死亡组剧毒高毒类农药、就诊时间和APACHE-Ⅱ评分明显高于生存组(P<0.05),呕吐时间和胆碱酯酶活力明显低于生存组(P<0.05),心率和血压差异无统计学意义(P>0.05)。剧毒高毒药物,就诊时间>30 min,APACHE-Ⅱ评分>20分和胆碱酯酶活力<2 000 U/L是急性重症有机磷农药中毒患者死亡的独立危险因素。结论:就诊时间较长、APACHE-Ⅱ评分较高和胆碱酯酶活力低的患者死亡风险高。Objective:To investigate the factors affecting the prognosis of patients with acute severe organophosphorus pesticide poisoning.Methods:60patients with acute severe organophosphorus pesticide poisoning were selected.We compared the clinical data of the death group and the survival group.Results:In the death group,highly toxic pesticides,treatment time and APACHE-Ⅱscore were significantly higher than the survival group(P<0.05);vomiting time and cholinesterase activity were significantly lower than the survival group(P<0.05);the blood pressure and heart rate had no significant difference(P>0.05).Highly toxic drugs,treatment time more than30minutes,APACHE-Ⅱscore more than20points and cholinesterase activity less than2000U/L were independent risk factors of death of patients with acute severe organophosphorus pesticide poisoning.Conclusion:The risk of death of patients with long treatment time,high APACHE-Ⅱscore and low cholinesterase activity was high.

关 键 词：有机磷中毒 预后分析 APACHE-Ⅱ评分 胆碱酯酶活力 

分 类 号：R595.4[医药卫生—内科学]