腰椎终板Modic改变与椎间盘退变的相关性的定量MRI研究  

Quantitative MR imaging study of association between lumbar vertebral endplate Modic changes and intervertebral disc degeneration

作　　者：龚静山[1] 梅东东 朱进[1] 周阳泱[1] GONG Jing-shan;MEI Dong-dong;ZHU Jin;ZHOU Yang-yang

机构地区：[1]深圳市人民医院(暨南大学第二临床医学院)放射科,深圳518020

出　　处：《磁共振成像》2017年第7期514-518,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：深圳市科技计划项目(编号:JCYJ2014041622811967)~~

摘　　要：目的探讨腰椎终板Modic改变与相邻椎间盘退变的相关。材料与方法于66例腰椎结构和定量MR图像上,采用Pfirrmann分级半定量和测量椎间盘T2和T2*值定量评价椎间盘退变程度,比较腰椎终板Modic改变与椎间盘Pfirrmann评分、T2和T2*值的相关性。结果 66例患者中,14例患者(21.2%)终板有19个椎间盘相邻的终板有Modic改变,包括2个椎间盘相邻的终板为Modic 1型改变,17个椎间盘相邻的终板为Modic 2型改变。正常终板、Modic 1型终板和Modic 2型终板相邻椎间盘的Pfirrmann评分分别为2.40±0.96、4.00±1.41和4.12±1.27,T2值分别为(95.38±51.88)、(70.50±36.06)和(58.65±38.47)ms,T2*值分别为(34.43±19.16)、(24.00±1.41)和(28.65±23.39)ms,差异均有统计学意义(P值分别为0.000、0.000和0.023)。Modic 2型终板相邻的椎体伴有严重的椎间盘退变(Pfirrmann评分升高,T2和T2*值降低),与正常终板相邻的椎间盘比较,差异具有统计学意义(P值分别为0.000、0.000和0.006)。结论腰椎终板Modic改变与相邻的椎间盘退变具有相关性,终板改变和椎间盘退变应作为腰椎退变的整体改变。Objective:To investigate the relationship between vertebral endplate Modical changes and adjacent intervertebral disc degeneration.Materials and Methods:Lumbar structure and quantitative MR images of66patients were retrospectively analyzed.Disc degeneration was semi-quantitatively assessed using Pfirrmann grading system and quantitatively assessed using T2and T2values.Association between Pfirrmann scores,T2and T2*values of intervertebral discs with adjacent endplate Modic changes was analyzed.Results:Nineteen intervertebral discs with adjacent endplate Modic changes were detected in fourteen patients(14/66,21.2%),which included2discs with Modic type1changes and17discs with type2changes.Pfirrmann scores of the discs adjacent to normal endplates,Modic type1endplates and Modic type2endplates were2.40士0.96、4士1.41and4.12士1.27,respectively.T2values were(95.38士51.88)ms,(70.50士36.06)ms and(58.65士38.47)ms.T2*values were(34.43士19.16)ms,(24.00士1.41)ms and(28.65±23.00)ms.The differences of disc Pfirrmann scores,T2and T2values among different endplate changes were statistical significant with P values of0.000,0.000and0.023,respectively.Comparing to discs adjacent to normal endplates,discs adjacent to Modic type2endplates had severe degeneration with increased Pfirrmann scores and decreased T2and T2*values.The differences were statistical significant(P values were0.000,0.000and0.006,respectively).Conclusions:Modic changes of vertebral endplate are associated with adjacent intervertebral disc degeneration.Both of them should be regarded as a facet of the"whole-organ"pathologic conditions in the Objective:To investigate the relationship between vertebral endplate Modical changes and adjacent intervertebral disc degeneration.Materials and Methods:Lumbar structure and quantitative MR images of66patients were retrospectively analyzed.Disc degeneration was semi-quantitatively assessed using Pfirrmann grading system and quantitatively assessed using T2and T2values.Association between Pfirrmann scores,T2and T2*value

关 键 词：椎间盘退化 腰椎 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681.53[医药卫生—诊断学]