Recent Progress in Diagnosis Methods for Latent Tuberculosis Infection and Its Clinical Applications  

作　　者：Ling Zhou 

机构地区：[1]Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital

出　　处：《国际感染病学（电子版）》2015年第3期69-74,共6页Infection International(Electronic Edition)

摘　　要：Most people with latent Mycobacterium tuberculosis infection can partly develop active tuberculosis (TB). Therefore, diagnosis of this condition bears significance in early TB prevention. To date, the main methods for diagnosis of latent TB infection (LTBI) include tuberculin skin test and interferon γ release test. These two methods feature their own advantages and disadvantages. Although new diagnostic markers continually emerge, no uniform diagnostic criteria are available for TB detection. This study summarizes several methods for diagnosis of LTBI and new related markers and their application value in clinical practice.Most people with latent Mycobacterium tuberculosis infection can partly develop active tuberculosis(TB). Therefore, diagnosis of this condition bears significance in early TB prevention. To date, the main methods for diagnosis of latent TB infection(LTBI) include tuberculin skin test and interferon γ release test. These two methods feature their own advantages and disadvantages. Although new diagnostic markers continually emerge, no uniform diagnostic criteria are available for TB detection. This study summarizes several methods for diagnosis of LTBI and new related markers and their application value in clinical practice.

关 键 词：MYCOBACTERIUM TUBERCULOSIS LATENT infection TUBERCULIN SKIN test INTERFERON-GAMMA release assays 

分 类 号：R52[医药卫生—内科学]