CPAP治疗婴幼儿非重症ARDS的疗效观察  

Clinical efficacy of continuous positive airway pressure ventilation in treatment of infantile acute respiratory distress syndrome

作　　者：黄葆莹[1] 蒋苏华[1] 庞永昌 何丽仪[1] Huang Baoying;Jiang Suhua;Pang Yongchang;He Liyi(Department of Pediatrics the First People's Hospital of Foshan City, Foshan 528000, China)

机构地区：[1]佛山市第一人民医院儿科,佛山528000

出　　处：《新医学》2017年第7期499-502,共4页Journal of New Medicine

摘　　要：目的探讨CPAP治疗婴幼儿非重症ARDS的临床疗效。方法选择60例非重症ARDS婴幼儿,分为观察组和对照组,每组各30例患儿,分别给予CPAP和面罩吸氧治疗,观察治疗前期(给氧2 h)、中期(给氧48~72 h)以及后期(撤机前半小时)2组患儿的心率、Sa O2/吸入氧浓度(S/F)、氧指数、血气分析p H值,并比较2组患儿的住院时间和气管插管率。结果治疗早期,2组患儿各指标比较差异均无统计学意义(P均>0.05);治疗中期及后期观察组患儿的心率、S/F、氧指数、血气分析p H值均比对照组改善(P均<0.05)。与对照组患儿比较,观察组患儿的用氧时间及住院时间较短、气管插管率较低(P均<0.01)。结论 CPAP治疗ARDS患儿可改善其缺氧状态,有效提高预后。Objective To evaluate the clinical efficacy of continuous positive airway pressure(CPAP)in the treatment of infantile acute respiratory distress syndrome(ARDS).Methods Sixty infants diagnosed with non-severe ARDS were randomly assigned into the observation(n=30)and control groups(n=30).In the observation group,patients received CPAP and those in the control group were treated with oxygen mask inhalation.The heart rate,Sa02/inspiratory oxygen concentration(S/F ratio),oxygenation index(01)and blood gas analysis of pH at2h,48-72h after oxygen inhalation,and30min before the termination of oxygen inhalation were observed.The length of hospital stay and tracheal intubation rate were statistically compared between two groups.Results At2h after oxygen inhalation,no statistical significance was identified in each parameter between two groups(all P>0.05).At48-72h after oxygen inhalation,and30min before the termination of oxygen inhalation,heart rate,S/F ratio,01and blood gas analysis of pH value in the observation group were significantly improved compared with those in the control group(all P<0.05).Compared with the control group,the length of hospital stay and tracheal intubation rate were considerably reduced in the observation group(both P<0.01).Conclusion CPAP can alleviate the anoxia status,enhance lung function and increase clinical prognosis in ARDS infants.

关 键 词：婴幼儿 急性呼吸窘迫综合征 持续气道正压通气 

分 类 号：R725.6[医药卫生—儿科]