磁共振动态定量扫描在鉴别腮腺肿瘤恶性度中的应用  

Application of Dynamic Quantitative MRI Scans in the Identification of the Malignant Degree of the Parotid Gland Tumor

作　　者：桑鋆智 李醒[2] 张天宇[3] 李卉[4] 吕伟扬 SANG Jun-zhi;LI Xing;ZHANG Tian-yu;LI Hui;LV Wei-yang(MRI Room the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar Heilongjiang 161000, China;Department of Ultrasound the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar Heilongjiang 161000, China;Department of CT the Second Affiliated Hospitalof Qiqihar Medical University, Qiqihar Heilongjiang 161000, China;Department of Electrophysiology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar Heilongjiang 161000, China)

机构地区：[1]齐齐哈尔医学院附属第二医院核磁共振室,黑龙江齐齐哈尔161000 [2]齐齐哈尔医学院附属第二医院超声科,黑龙江齐齐哈尔161000 [3]齐齐哈尔医学院附属第二医院CT室,黑龙江齐齐哈尔161000 [4]齐齐哈尔医学院附属第二医院电生理科,黑龙江齐齐哈尔161000

出　　处：《中国医疗设备》2017年第8期72-75,共4页China Medical Devices

摘　　要：目的研究动态增强磁共振扫描(Dynamic Enhanced MRI,DCE-MRI)定量参数在诊断良恶性腮腺肿瘤中的情况分析。方法选取2016年8月~2017年1月间于我院行DCE-MRI扫描并进行手术病理确诊的患者共90例,包括肿块112个。分析各病理类型的肿块的定量参数数据:K^(trans)、K_(ep)、Ve,同时分析DCE-MRI定量参数在良恶性肿瘤诊断的灵敏度和特异度。结果腮腺淋巴瘤、腮腺恶性肿瘤、腮腺混合瘤和其余各类良性病灶的K^(trans)值、K_(ep)值和Ve值间的差异具有统计学意义(c2=11.23;34.56;44.79,P<0.01);恶性肿瘤病灶较混合瘤病灶的K^(trans)值和K_(ep)值明显较高,而K_(ep)值明显较淋巴瘤低。恶性肿瘤与多形性腺瘤规定阈值K^(trans)=0.31 min^(-1),恶性肿瘤病灶的确诊灵敏度为74.31%。特异度为78.92%;恶性肿瘤与腺淋巴瘤比较规定阈值K_(ep)=0.96 min^(-1)、Ve=0.364,恶性肿瘤病灶的确诊灵敏度为66.32%,特异度为69.26%。结论 DCE-MRI中定量参数扫描效果准确,在诊断良恶性腮腺病变中有着较好的效果,值得临床推广使用。Objective We aimed to study the application of quantitative parameters of dynamic enhanced MRI scans(DCE MRI)in the diagnosis of benign and malignant parotid gland tumors.Methods A total of90cases with112lumps who underwent DCE-MRI from August2016to January2016in our hospital were included in this study.The quantitative parameters of pathological data of lumps such as Ktrans,Kep and Ve were analyzed.In the meanwhile,the sensitivity and specificity of the DCE-MRI diagnosis were also evaluated.Results Compared with various benign lesions,the differences of Ktrans value,Kep value and Ve value of the parotid gland lymphoma,parotid malignancy and parotid gland mixed tumor were statistically significant(c2=11.23,34.56and44.79respectively,P<0.01).The Ktrans and Kep values of malignant tumor lesions were significantly higher than those of mixed tumors,while the Kep values was significantly lower than lymphoma.The threshold of malignant neoplasms and pleomorphic adenomas was Ktrans=0.31min-1.The diagnostic sensitivity and specificity of malignant tumor lesions were74.31%and78.92%,respectively.Malignant neoplasms and adenocarcinomas were compared with thresholds of Kep=0.96min-1and Ve=0.364.The diagnostic sensitivity and specificity of malignant tumor were66.32and69.26respectively.Conclusion DCE-quantitative parameters in MRI scanning is worthy to be used in the clinical diagnosis of benign and malignant parotid gland lesions with high accurate.

关 键 词：动态磁共振成像 腮腺病变 定量扫描 灵敏度 特异度 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.8[医药卫生—诊断学]