2%利多卡因局麻导尿对急性心肌梗死男性患者血流动力学指标的影响  

Effect of 2% lidocaine local anesthesia on hemodynamics in male patients with acute myocardial infarction

作　　者：陈韫琴[1] 雷玲[1] 苏佩洁[1] 刘力新[1] CHEN Wenqin;LEI Ling;SU Peijie;LIU Lixin(Critical Care Medicine, Xiaolan Hospital Affiliated to Southern Medical University, Zhongshan 528415, China)

机构地区：[1]南方医科大学附属小榄医院重症医学科,广东中山528415

出　　处：《中国医药科学》2017年第15期16-19,共4页China Medicine And Pharmacy

基　　金：广东省中山市医学科研基金项目(2014A020196)

摘　　要：目的探讨2%利多卡因局麻导尿对急性心肌梗死男性患者血流动力学指标的影响。方法将72例在我院接受治疗的男性急性心肌梗死需留置导尿患者随机分为对照组和试验组,每组36例。其中对照组患者给予常规导尿操作,试验组患者在行常规导尿术前对患者尿道内预灌注2%利多卡因进行局麻。比较两组患者一次导尿成功率及导尿术前及导尿术后即刻血流动力学指标变化情况。结果试验组患者一次导尿的成功率明显高于对照组,患者尿道黏膜损伤发生率也明显低于对照组(P<0.05);导尿操作前两组患者的收缩压(SBP)、舒张压(DBP)及心率(HR)比较无显著性差异(P>0.05),操作后即刻对照组患者SBP、DBP及HR均明显升高(P<0.05),而试验组患者则无显著性变化(P>0.05),且两组比较差异显著(P<0.05);试验组患者导尿术时的疼痛程度明显高于对照组患者,且导尿术及留置尿管操作诱发心绞痛发生率明显高于对照组(P<0.05)。结论对男性急性心肌梗死患者行导尿术前给予2%利多卡因局麻具有减轻疼痛、增加润滑效果和导向作用,对患者尿道黏膜造成的损伤小,且操作简单方便,值得临床推广应用。Objective To investigate the effect of2%lidocaine local anesthesia on hemodynamics in malepatients with acute myocardial infarction(AMI).Methods72cases of Patients with acute myocardial infarctionneeding retention catheterization were randomly divided into the control group and the experimental group,36casesin each group.The patients in the control group received routine catheterization,the patients in the experimentalgroup received local anesthesia with2%lidocaine before the routine catheterization.The success rate of the firstcatheterization and the hemodynamic changes before and after the catheterization were compared between the twogroups.Results The success rate of primary catheterization of the experimental group was higher than that than ofthe control group,and the rate of urethral mucosal injury was also lower than that of the control group(P<0.05).Before catheterization,the systolic pressure(SBP),diastolic blood pressure(DBP)and heart rate(HR)of the two groupswere not significantly different(P>0.05),immediately after operation,the SBP,DBP and HR in the control groupwere significantly increased(P<0.05),but there were no significant changes in the experimental group(P>0.05),and the differences between the two groups were significant(P<0.05).The degree of pain during catheterizationof the experimental group was higher than of the control group,and the incidence of angina pectoris caused bycatheterization and indwelling catheter was significantly highe r than that of the control group(P<0.05).ConclusionFor male patients with acute myocardial infarction,the application of2%lidocaine before catheterization can relievepain,it has the effects of lubrication and guide,and the damage of urethra mucosa is small,and the operation is simpleand convenient,so it is worthy of clinical application.

关 键 词：急性心肌梗死 导尿术 利多卡因 局部麻醉 

分 类 号：R542.2[医药卫生—心血管疾病]