疼痛治疗病区镇痛药和辅助性镇痛药应用情况分析  

Analysis on the application of analgesics and adjuvant analgesics in pain management ward

作　　者：王伟兰[1] 路桂军[2] WANG Wei-lan;LU Gui-jun(Department of Pharmacy, PLA General Hospital, Beijing 100853, China;Department of Pain Management, PLA General Hospital, Beijing 100853, China)

机构地区：[1]解放军总医院药学部,北京100853 [2]解放军总医院疼痛治疗病区,北京100853

出　　处：《中国药物应用与监测》2017年第4期232-235,共4页Chinese Journal of Drug Application and Monitoring

基　　金：解放军总医院临床科研扶持基金项目(2015FC-TSYS-1039)

摘　　要：目的:对我院疼痛治疗病区患者的疼痛治疗进行回顾性分析,以期为临床合理用药提供参考。方法:利用医院HIS系统收集2016年1月–6月疼痛治疗科所有接受疼痛治疗的住院患者的临床病例,分析统计患者的临床特点、镇痛药和辅助性镇痛药使用情况。结果:共计223例患者接受了疼痛治疗,其中男性患者和女性患者,≥60岁和<60岁患者应用镇痛及辅助性镇痛药物的数量相似,性别、年龄两方面的差异均无统计学意义(P>0.05),而在癌痛患者应用镇痛及辅助镇痛药物的数量要高于非癌痛患者,差异有统计学意义(P<0.05)。在不同的镇痛及辅助性镇痛药物中,抗惊厥药、非甾体抗炎药、中枢性镇痛药占所有镇痛及辅助性镇痛药物的比例最高,依次为24.80%、12.51%、10.94%;而普瑞巴林、曲马多、盐酸乙哌立松为患者使用频率最高的药物。结论:我院疼痛治疗病区多为慢性难治性疼痛患者,镇痛药物和辅助性镇痛药物的联合应用取得了较好的镇痛效果,建议临床在应用时应掌握各种药物的使用注意事项,以防范潜在的用药风险。Objective:To retrospectively analyze the treatment of pain patients in pain management ward of our hospital,and provide reference for rational drug use in clinic.Methods:All clinical cases and drug information of pain patients from Januaryto June in2016were collected by the HIS system of the hospital,and application of analgesics and adjuvant analgesics was analyzed.Results:A total of223patients accepted the analgesic treatment.The number of analgesic and adjuvant analgesic drugs was similarbetween male patients and female patients,also between≥60and<60years old patients,without significant difference(P>0.05).Butthe number of analgesic and auxiliary analgesic drugs used in cancer pain patients was higher than that of non-cancer pain patients,with significant difference(P<0.05).The top three categories of analgesics and adjuvant analgesics were anticonvulsants(24.80%),NSAIDs(12.51%)and central analgesics(10.94%).The top three analgesics and adjuvant analgesics in terms of use frequency werepregabalin,tramadol and eperisone hydrochloride.Conclusion:Good analgesic effect was received by combination of analgesicdrugs and adjuvant analgesic drugs,while attentions and potential risks of drugs also should be mastered.

关 键 词：疼痛治疗病区 镇痛药 辅助性镇痛药 分析 

分 类 号：R971.1[医药卫生—药品]