佳尔纳与维生素C注射液配伍稳定性的研究  

Study on the Stability of Metronidazole Disodium Phosphate for injection match with Vitamin C Injection

作　　者：周国强 ZHOU Guo-qiang(Suzhou Wujiang District Hospital of Traditional Chinese Medicine, Suzhou 215221, China)

机构地区：[1]江苏省苏州市吴江区中医医院,江苏苏州215221

出　　处：《中国医药指南》2017年第23期18-20,共3页Guide of China Medicine

摘　　要：目的建立佳尔纳与维生素C注射液的配伍稳定性考察方法。方法双波长紫外分光光度法。结果甲硝唑浓度为5~10μg/mL,维生素C浓度为5~10μg/mL,浓度C与吸收度A均呈良好的线性关系,回归方程分别为:C=18.80A+0.1315(r=0.9999)及C=11.78A-0.0286(r=0.9999)。平均回收率分别为99.54%及99.95%。结论本法原理简单,操作简便,重复性好,结果准确,可作为稳定性的考察方法。Objective To establish a method for the stability of Disodium phosphate for injection match with Vitamin C injection.Method Dual-wavelength spectrophotometry.Results The concentration of metronidazde Disodiun phosphate range from5-10μg/mL,and that of Vitamin C from5-10μg/mL,the linear regression equation was C=18.80A+0.1315(r=0.9999),and C=11.78A-0.0286(r=0.9999).The average recovery rate were99.54%and99.95%respectively.Conclusion The method is simple and accurate which can be used for stability studying Metronidazole Disodium phosphate for injection match with Vitamin C injection.

关 键 词：双波长紫外分光光度法 甲硝唑 维生素C 

分 类 号：R927.11[医药卫生—药学]