血型不规则抗体筛查用于预防和降低临床无效输血发生的效果观察  

Screening of blood group irregular antibody for the prevention and reduction of clinical ineffective transfusion

作　　者：沙吉代木.买买提 胡国龙[1] 阿先古丽.阿不力孜 Shajidaimu.MAIMAITI;Guolong HU;Axianguli.ABULIZI(Department of Transfusion,Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China;Department of Clinical Laboratory, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, China)

机构地区：[1]新疆医科大学附属肿瘤医院输血科,乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院检验科,乌鲁木齐830011

出　　处：《临床检验杂志（电子版）》2017年第1期20-22,共3页Clinical Laboratory Journal(Electronic Edition)

基　　金：新疆医科大学创新基金项目(No.XYDCX201469)

摘　　要：目的利用血型不规则抗体筛查,以预防和降低临床上的无效输血,并观察临床效果。方法选取2015年10月-2016年10月间我院接诊的献血者和接受血液者,各1,000例,采用微柱凝胶法,血型不规则抗体筛查Ⅰ号、Ⅱ号、Ⅲ号细胞和抗体鉴定谱细胞对血液中的血型不规则抗体进行筛查。结果 2,000例检测者中,含有血型不规则抗体的81例,阳性几率为4.1%。其中献血者中血型不规则抗体阳性者31例,阳性几率为3.1%;受血者中血型不规则抗体有50例,阳性几率为5.0%。结论人群中血型不规则抗体阳性几率虽然较低,但仍然存在。我院采取血型不规则抗体筛查,可有效预防和降低临床输血无效的发生,并取得了较好的临床效果。Objective To prevent and reduce the clinical ineffective blood transfusion by using bloodgroup irregular antibody screening and observe the clinical effect.Methods From October2015to October2016,2,000cases of blood donors and blood recipients were collected.Microarray gel method and blood type irregularantibody were used to screen cells I,II,III and antibody identification cells were screened for blood group irregularantibodies in their blood.Results Among the2,000cases,81cases had irregular blood type antibody andthe positive probability was4.1%.Among them,31cases were positive for blood group irregularities in blooddonors and the positive probability was3.1%;50cases of blood group irregularities were50.0%and the positiveprobability was5.0%.Conclusion The positive probability of blood group irregular antibody in the populationis low,but still exists.Blood type irregular antibody screening could effectively prevent and reduce the occurrenceof clinical transfusion ineffective,and achieved good clinical results.

关 键 词：血型不规则抗体筛查 无效输血 临床效果 

分 类 号：R446.6[医药卫生—诊断学] R457.1[医药卫生—临床医学]