思他宁联合手术治疗结肠癌合并肠梗阻的临床效果分析  

Analysis on the clinical effect of sirolimine combined with surgical operation on the treatment of colonic cancer complicated with intestinal obstruction

作　　者：吴骏飞 方复 毛华辉 卢国春 WU Jun-fei;FANG Fu;MAO Hua-hui;LU Guo-chun(General Surgery,Tonglu County First People's Hospital, Hangzhou 311500,China)

机构地区：[1]桐庐县第一人民医院普外科,浙江杭州311500

出　　处：《中国生化药物杂志》2017年第9期205-206,共2页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的分析思他宁联合手术治疗结肠癌合并肠梗阻的临床效果。方法选取2016年11月～2017年5月来我院就医的结肠癌合并肠梗阻患者120例作为本次研究的对象，通过动态化随机颜色球抽取的方法将其分为观察组和对照组。对照组予以I期结肠切除吻合术，观察组予以思他宁联合I期结肠切除吻合术治疗，对比2组患者手术各项指标、并发症发生情况的差异性。结果观察组患者的术中出血量、手术时间与对照组患者比较，差异无统计学意义；观察组患者肛门排气恢复时间为（3.01±0.41）d、住院时间为（10.11±1.21）d、并发症发生例数为2例，对照组患者肛门排气恢复时间为（5.41±0.84）d、住院时间为（16.33±2.05）d、并发症发生例数为10例，差异具有统计学意义（P＜0.05）。结论思他宁联合手术治疗结肠癌合并肠梗阻患者具有一定的应用价值。Objective To analyze the clinical effect of combination therapy of somatidine on colorectal cancer with intestinal obstruction.Methods120patients with colorectal cancer complicated with intestinal obstruction who were treated with Yujiang County Hospital of ZhejiangProvince from November2016to May2017were selected as the subjects of this study and divided into observation group by dynamic randomcolor ball extraction method And control group.The rats in the control group were given stage I colonic resection and anastomosis.The observationgroup was treated with somatanine combined with stage I colonic resection and anastomosis.The differences of the indexes and complication werecompared between the two groups.Results There was no significant difference in the operation time between the two groups(3.01±0.41)days andthe hospitalization time(10.11±1.21)days in the observation group,and the time of operation was significantly higher than that of the control group(5.41±0.84)days,the hospitalization time was(16.33±2.05)days,the number of complications occurred in10cases,the difference was more thanthat in the control group Significantly(P<0.05).Conclusion Si Tanning combined with surgical treatment of colorectal cancer with intestinalobstruction has a certain value.

关 键 词：思他宁 结肠癌 肠梗阻 

分 类 号：R656.9[医药卫生—外科学]