静脉注射右美托咪啶辅助全身麻醉的有效性及安全性分析  

Efficacy and safety of intravenous dexmedetomidine in general anesthesia

作　　者：田育斌[1] TIAN Yu-bin(BaojiMaternal and Child Care Service Centre ,Baoji 721000, China)

机构地区：[1]陕西省宝鸡市妇幼保健院,陕西宝鸡721000

出　　处：《中国生化药物杂志》2017年第9期236-237,239,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨右美托咪啶联合舒芬太尼在患者全身麻醉过程中的应用效果和安全性。方法选用2015年5月～2017年5月期间在陕西省宝鸡市妇幼保健院实施全身麻醉的44例患者为研究对象，均分为对照组和观察组，对照组应用常规麻醉，观察组在对照组麻醉基础上辅助应用静脉注射右美托咪啶，对比分析2组患者苏醒时间、自主呼吸恢复时间、气管拔除时间、不良反应发生情况。结果2组患者的苏醒时间、自主呼吸恢复时间、气管拔除时间进行比较，观察组明显更低，组间比较，差异具有统计学意义（Ρ＜0.05）；2组患者的不良反应发生率分别为9.09%和31.82%，观察组明显更低，组间比较，差异具有统计学意义（Ρ＜0.05）。结论静脉注射右美托咪啶在患者全身麻醉过程中的应用效果显著，患者的苏醒时间、气管拔除时间明显缩短，提高了患者的安全性，值得推广应用。Objective To evaluate the efficacy and safety of intravenous dexmedetomidine in the anesthesia of general anesthesia.MethodsIt selected44patients from May2015to May2017during our hospital general anesthesia for the study.They were divided into two groups:control group and observation group.Routine anesthesia and intravenous injection of dexmedetomidine were used.It compared the recovery time,spontaneous breathing recovery time,extubation time and adverse reactions in the two groups.Results The recovery time,spontaneous breathingrecovery time and tracheal extubation time of the two groups were significantly lower than that of the observation group.The difference betweenthe two groups was statistically significant(Ρ<0.05).The incidence of adverse reactions in the two groups was9.09%and31.82%,respectively.Thedifference between the two groups was statistically significant(Ρ<0.05).Conclusion Intravenous dexmedetomidine is effective in the anesthesia ofgeneral anesthesia.The recovery time and extubation time of the patients were significantly shortened,and the safety of the patients was improved.Therefore,based on the above advantages,it is worthy of popularization and application.

关 键 词：静脉注射 右美托咪啶 全身麻醉 有效性 安全性 

分 类 号：R614.2[医药卫生—麻醉学]