《古今名医临证金鉴·中风卷》用药规律研究  

Study on Medication Rules of Treatment of Stroke in Gu Jin Ming Yi Lin Zheng Jin Jian Zhong Feng Juan

作　　者：彭智远 曹雯[1] 刘旺华[1] 李花[1] 钟银玲[1] 周翠玲[1] 张婕[1] PENG Zhi-yuan;CAO Wen;LIU Wang-hua;LI Hua;ZHONG Yin-ling;ZHOU Cui-ling;ZHANG Jie(Hunan University of Chinese Medicine, Changsha 410208, China)

机构地区：[1]湖南中医药大学,湖南长沙410208

出　　处：《中国中医药信息杂志》2017年第10期81-84,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(81202632;81373702;81473567);教育部博士点基金(20124323120003);湖南省自然科学基金(13JJ3097);湖南省教育厅科研项目(14B134);湖南省高校创新平台开放基金(15K092)

摘　　要：目的分析《古今名医临证金鉴·中风卷》用药规律,为临床提供参考。方法查阅《古今名医临证金鉴·中风卷》收录的历代名医治疗中风疗效确切的处方,采用Excel2003建立数据库,统计用药频次。采用SPSS17.0统计软件对常用药物进行聚类分析,以树状图展示结果。结果共纳入36位名医治疗中风的处方112首,涉及药物204味,用药频次1169次,其中高频药物(>10次)有白芍、牛膝、当归、法半夏、茯苓等。高频药物类别有补虚药(22.58%)、平肝息风药(12.31%)、活血化瘀药(11.89%)、清热药(11.46%)及化痰止咳平喘药(8.72%)等。聚类分析表明高频药物(>10次)可聚为6类。结论《古今名医临证金鉴·中风卷》以补虚药为主,配以平肝息风药、活血化瘀药、清热药及化痰止咳平喘药等治疗中风,可指导临床。Objective To analyze the medication rules of the treatment of stroke in Gu Jin Ming Yi Lin Zheng Jin Jian Zhong Feng Juan;To provide references for the clinical treatment.Methods Prescriptions with confirmed efficacy of famous TCM doctors in the history in Gu Jin Ming Yi Lin Zheng Jin Jian Zhong Feng Juan was searched.Excel2003was used to establish database to analyze medication frequency.SPSS17.0statistical software was used to conduct cluster analysis,and tree view was used to show results.Results Totally112prescriptions for the treatment of stroke of36famous TCM doctors were included in the study,including204kinds of Chinese materia medica and1169times of medication frequency.The high-frequency medicines(>10times)were Paeoniae Radix Alba,Achyranthis Bidentatae Radix,Angelicae Sinensis Radix,Pinelliae Rhizoma Praeparatum,and Poria.The high-frequency medicine categories were tonifying deficiency medicine(22.58%),pacifying liver and wind medicine(12.31%),activating blood and dispelling stasis medicine(11.89%),clearing heat medicine(11.46%)and dissipating phlegm,cough and asthma medicine(8.72%).Cluster analysis showed that high-frequency medicine(>10times)could be clustered as6categories.Conclusion Gu Jin Ming Yi Lin Zheng Jin Jian Zhong Feng Juan focuses on tonifying deficiency medicine,accompanied with pacifying liver and wind medicine,activating blood and dispelling stasis medicine,clearing heat medicine and dissipating phlegm,cough and asthma medicine,which can be used to guide clinic.

关 键 词：古今名医临证金鉴 中风 用药规律 聚类分析 

分 类 号：R2-05[医药卫生—中医学] R255.2