曲马多联合芬太尼超前镇痛对老年术后认知功能障碍的影响分析  

Tramadol Combined With Fentanyl in Preemptive Analgesia Effects on Postoperative Cognitive Dysfunction in Elderly Patients

作　　者：于萍[1] YU Ping(Department of Anesthesiology, The Second Affiliated Hospital of Baotou Medical College, Baotou Inner Mongolia 014030, China)

机构地区：[1]包头医学院第二附属医院麻醉科,内蒙古包头014030

出　　处：《中国卫生标准管理》2017年第21期120-122,共3页China Health Standard Management

摘　　要：目的探讨曲马多+芬太尼超前镇痛对老年患者的治疗效果。方法选取至我院就诊的82例老年骨科患者(2014年5月21日—2016年5月21日),两组患者均给予静脉自控镇痛治疗,实验组在此基础上给予曲马多+芬太尼超前镇痛治疗,对比两组治疗效果。结果实验组与常规组的POCD发生率分别为24.39%与41.46%,差异具有统计学意义,P<0.05;比较两组术后的MMSE评分,差异具有统计学意义,P<0.05。结论对老年手术患者给予曲马多+芬太尼超前镇痛治疗便于降低POCD的发生率,改善患者认知功能。Objective To explore the effect of tramadol+fentanyl on preemptive analgesia effects of elderly patients.Methods82elderly patients in department of orthopedics(from May21,2014to May21,2016)were selected from our hospital,and two groups were given intravenous patient-controlled analgesia.The experimental group on the basis that given tramadol+fentanyl analgesic treatment,and the therapeutic effect of two groups was compared.Results The incidence of POCD in the experimental group and the routine group was24.39%and41.46%,respectively,and the difference was statistically significant,P<0.05;The MMSE scores of the two groups were compared,the difference was statistically significant,P<0.05.Conclusion The treatment of the patients with tramadol+fentanyl can reduce the incidence of POCD and improve the cognitive function of patients.

关 键 词：老年 认知功能障碍 超前镇痛 曲马多 芬太尼 

分 类 号：R614[医药卫生—麻醉学]