体外研究机械通气流速触发与压力触发对持续喷射雾化器的影响  

Effects of Flow Rate Trigger and Pressure Trigger on Continuous Spray Atomizer in Mechanical Ventilation

作　　者：周全[1] 唐丽玲[1] 杨柳[1] 鲍娟[1] 鲁卫华[1] 

机构地区：[1]皖南医学院附属弋矶山医院,安徽芜湖241000

出　　处：《长江大学学报（自然科学版）》2017年第16期48-50,共3页Journal of Yangtze University(Natural Science Edition)

基　　金：皖南医学院校中青年科研基金项目(WK2016F31);全国高等医学教育学会护理教育分会第二轮科学研究项目(GJHLQZ160018)

摘　　要：目的:比较压力触发与流速触发在体外模拟机械通气患者非同步持续喷射雾化吸入影响的效果。方法:本研究分流速触发和压力触发两组,每组15例。雾化时长30min,雾化动力源为中心供氧8L/min,模式为容量控制V-A/C模式,潮气量设置为500mL,送气流速为方波,吸气时间1s,PEEP(positive end expiratory pressure)5cmH2O,呼吸频率20次/min。结果:压力触发组和流速触发组在雾化吸入完毕后,死腔容量、管道损耗、雾化后雾化器重量无明显差异(P>0.05)。但压力触发组在模拟肺前后差和过滤器前后差方面体现出差异性,压力触发组在模拟肺沉积量多于流速触发组,在呼出端浪费的气溶胶少于流速组。结论:压力触发组在模拟肺内沉积量和呼出端过滤器截流量优于流速触发组(P<0.01),在提高雾化效率和降低因雾化吸入带来呼吸机的损害风险方面有明显的优势。Objective:To compare the effect of pressure triggering and flow rate triggering on the effect of non-synchronous continuous spray atomization in vitro in simulated mechanical ventilation patients.METHODS:In this study,shunt triggering and pressure triggering were performed in two groups of 15 patients.Atomization time 30 min,atomization power source for the central oxygen supply 8L/min,the mode for the capacity control VA/C mode,tidal volume set to 500 ml,air flow rate for the square wave,inspiratory time 1s,PEEP 5H2 O,breathing frequency 20per/Score.Results:There was no significant difference in the volume of dead space,the loss of pipeline and the weight of atomizer after atomization in the trigger group and flow rate group(P>0.05).However,in the pressure-triggered group,there were differences in the anteroposterior difference between the simulated lungs and the difference between the front and the back of the filter.The pressure triggering was less than the flow rate group in the simulated lung volume,and the aerosol was less than the flow rate group.Conclusion:In the pressure-triggered group,the amount of deposition in the simulated lung and the interception of the exhaled filter were better than those in the flow rate triggering group(P<0.01),which was significant in improving the atomization efficiency and reducing the risk of damage caused by the inhalation of the ventilator Advantage.

关 键 词：流速触发 压力触发 非同步机械通气 雾化吸入 连续喷射 

分 类 号：R459.6[医药卫生—治疗学] R473.5[医药卫生—临床医学]