肾脏血氧水平依赖性成像研究进展  

Progress of blood oxygen level-dependent(BOLD) MRI in the kidney

作　　者：黄海波[1] HUANG Hai-bo(Department of Medical Imaging, 303rd Hospital of PLA, Nanning 530021, China)

机构地区：[1]解放军第303医院医学影像科,南宁530021

出　　处：《磁共振成像》2017年第8期636-640,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：广西卫生计生委自筹经费课题(编号:Z2016518);解放军第303医院青年基金重点项目(编号:2016008)~~

摘　　要：肾脏是机体保持内环境稳定、调节水和电解质平衡状态、排出体内代谢物的关键器官,肾实质氧合状态在其生理功能发挥、疾病发生发展中具有重要意义。血氧水平依赖性成像作为无创性评价肾内氧代谢功能技术,可实现生理研究从解剖展示向代谢、功能和分子水平迈进,对肾病诊断、鉴别与疗效评估发挥日益明显的作用,本文就近年血氧水平依赖磁共振成像对肾脏研究展开综述。Kidney operates an important organ remaining the homeostasis,the waterelectrolytebalance,and discharging the metabolites in vivo,while the oxygenantionplays a key role in renal function and disorders.Blood oxygen level-dependentmagnetic resonance imaging(BOLD MRI)is a non-invasive functional technologyto evaluate the renal oxygen,which can not only display the morphological structureimaging,but also investigate the metabolism,the function,and the molecularlevel of the kidneys,up to now,it has been made great progresses in the diagnosis,the differentiation,and the therapeutic response of nephropathy.This article willreview the clinical progresses with BOLD MRI of the kidneys in the past few years.

关 键 词：肾脏 血氧水平依赖 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R692[医药卫生—诊断学]