超声血流指标联合孕中期血清HCG观察胎盘功能  

Ultrasonic Blood Flow Index Combined with Serum β-HCG in Mornitoring the Function of Placenta during Pregnancy

作　　者：黄燕玲[1] 陆永萍[1] 他林昆[1] 徐飞[1] 张琼[1] HUANG Yan-Ling;LU Yong-ping;TA Lin-kun;XU Fei;ZHANG Qiong(Dept. of Ultrasound,The 2nd People’s Hospital of Yunnan Province,Kunming Yunnan 650021,Chian)

机构地区：[1]云南省第二人民医院,昆明医科大学第四附属医院超声科,云南昆明650021

出　　处：《昆明医科大学学报》2017年第6期102-107,共6页Journal of Kunming Medical University

基　　金：云南省应用基础研究基金资助项目(2013FZ192)

摘　　要：目的探讨如何预测并有效定量评判胎盘功能.方法收集研究对象1 157例,超声测量胎盘血流参数;观察胎盘绒毛血管;记录孕妇血清游离β-HCGMoM值;记录新生儿体长、体重和生命体征综合评分.结果(1)血清游离β-HCGMoM值≥2.5宫内发育迟缓发生率显著增加;(2)宫内发育迟缓胎盘二、三级绒毛动脉管径细小,二、三级动脉数量明显减少;三级绒毛动脉显示率仅为38%,其显示率明显低于正常妊娠;胎盘三维能1量多普勒血流指数VI、FI、VFI低于正常妊娠.结论孕妇血清游离β-HCGMoM值≥2.5时,存在胎盘功能异常风险,胎盘绒毛血管及胎盘三维能量多普勒血流指数VI、FI、VFI可定性及定量评价胎盘功能.Objective To monitor placental function by using the ultrasonic blood flow index andserumβ-HCG.Methods From May2012to December2015in our hospital,1053cases of prenatal puerperaswere given placenta vascularization index(VI),blood flow index(FI)and vascularization-blood flow index(VFI)measurement by GE E8three-dimensional ultrasound at the same time,receivedβ-HCG levels test byusing the method of chemiluminescence.Postpartum neonatal body length,body weight and vital signscomprehensive score(Apgar score)were also recorded.Results There were131cases with serum freeβ-HCGMoM≥2.5,123cases with neonatal weight<2500g,8cases with normal weight;542cases with2.0P<β-HCGMoM<2.5,4cases with neonatal weight<2500g,438cases with normal weight;425cases with1.5P<β-HCG MoM<2.0,normal weight newborn;59cases withβ-HCG MoMvaluesP<1.5,normal birth weight.Theincidence of intrauterine retardation was93.8%in puerperas withβ-HCGMoM≥2.5,0.7%in puerperas with2.0<β-HCGMoM<2.0,and0%in puerperas with1.5<β-HCGMoM<2.0andβ-HCGMoM<1.5.The incidence ofintrauterine retardation in the group of pregnant women with serum freeβ-HCGMoM≥2.5was significantly greaterthan the control group(P<0.05).The placental villi vascular tree of1053cases was reconstructed by3d powerdoppler technology,and the primary,secondary and tertiary villi rate of artery in125cases in the study group was100%,73%,38%,in6cases in the study group was100%,86%and73%respectively,and in the controlgroup,the primary,secondary and tertiary villi rate of artery was100%,100%,85%,which weresignificantly higher than study group(P<0.05).Conclusions When2.5>serum freeβ-HCGMoM of pregnantwomen>2.0,the newborn may be associated with intrauterine retardation.Pregnant women serum freeβ-HCGMoM≥2.5,there is obviously increase in the incidence of neonatal intrauterine retardation.For those with intrauterine retardation,the placenta secondary and tertiary villi artery diameter is small,the number of arterydecreases significantly.Three-dimensional power doppler blood flow index of VI,FI

关 键 词：超声血流指标 Β-HCG 胎盘功能不全 

分 类 号：R445.1[医药卫生—影像医学与核医学]