持续盐水输注法与间隔盐水冲洗法在无肝素血液透析治疗中凝血情况的对比分析  

A contrastive analysis of continuous saline infusion and inter mitten saline flushing for blood coagulation in the treatment of hematodialysis without heparin

作　　者：王媛媛[1] 付航羽 WANG Yuan-yuan;FU Hang-yu(Department of Blood Purification, The First Hospital Affiliated to China Medical University, Shenyang 110001, China)

机构地区：[1]中国医科大学附属第一医院血液净化室,辽宁沈阳110001

出　　处：《中国医学装备》2017年第11期75-77,共3页China Medical Equipment

摘　　要：目的:比较间隔盐水冲洗法和持续盐水输注法在无肝素的血液透析治疗中凝血情况的观察与分析。方法:选取40例维持性血液透析治疗的患者进行回顾性分析,根据透析编号末位数字奇偶将患者分为对照组和观察组,每组20例,在无肝素法血液透析治疗中对照组采用间隔盐水冲洗法,观察组采用持续盐水输注法进行管路及透析器冲洗,比较两种冲洗方法在无肝素的血液透析治疗中凝血情况。结果:两组透析器凝血分级情况观察组明显优于对照组,两组Ⅰ~Ⅲ级凝血发生情况比较,其差异有统计学意义(x^2=27.517,P<0.05);两组患者治疗时的透析器使用时间比较,其差异有统计学意义(t=5.094,P<0.01)。结论:在管路及透析器的冲洗中,持续盐水输注法优于间隔盐水冲洗法,有助于提高透析器效能,降低透析器凝血的发生率,保证治疗过程的顺利。Objective:To compare the situation of blood coagulation of continuous saline infusion and inter mitten saline flushing in the treatment of hematodialysis without heparin.Methods:40patients with maintenance hemodialysis therapy were enrolled in retrospective analysis,and they were divided into observation group(20cases,their pipeline and dialyzer adopted continuous saline infusion)and control group(20cases,their pipeline and dialyzer adopted inter mitten saline flushing)according to serial number of dialysis.The blood coagulations of the two methods in the treatment of hematodialysis without heparin were compared.Results:The blood coagulation grading situation of dialyzer of observation group was obviously higher than that of control group.And the differences of I-III blood coagulation grading situation between the two groups were significant(x2=27.517,P<0.05).Besides,the difference of using time of dialyzer in treatment between the two groups were significant(t=5.094,P<0.01).Conclusion:In the flushing of pipeline and dialyzer,the continuous saline infusion method is superior to the inter mitten saline flushing,and it contributes to enhance the efficiency of dialyzer,and reduce occurrence rate of blood coagulation in dialyzer,and ensure the treatment process without any hitch.

关 键 词：血液透析 无肝素 凝血 间隔盐水冲洗法 持续盐水输注法 

分 类 号：R459.5[医药卫生—治疗学]