对比增强能谱成像与动态增强磁共振成像诊断乳腺癌的对比研究  

Comparative Study of Contrast-Enhanced Spectral Mammography and Dynamic ContrastEnhanced Magnetic Resonance Imaging in Diagnosis of Breast Cancer

作　　者：俞敏秋 李俊晨[1] YU Minqiu;LI Junchen(Department of Radiology, Changshu Affiliated Hospital of Nanjing University of Chinese Medicine, Changshu Jiangsu 215500, China)

机构地区：[1]南京中医药大学附属常熟医院放射科,江苏常熟215500

出　　处：《中国医疗设备》2017年第11期74-77,共4页China Medical Devices

摘　　要：目的回顾性分析对比增强能谱乳腺X线摄影(Contrast-Enhanced Spectral Mammography,CESM)与动态对比增强磁共振成像(Dynamic Contrast-Enhanced Magnetic Resonance Imaging,DCE-MRI)在乳腺癌诊断中的诊断性能。方法共有30例乳腺病变患者,均进行过CESM和DCE-MRI检查。采用双盲法和非随机研究。用配对T检验对病灶的大小和强化程度进行统计学分析。计算诊断敏感性、准确性和阳性预测值。并将CESM及DCE-MRI两种检查方法和病灶大小及强化程度进行多分类有序logistic回归统计分析。结果共鉴定出34例病灶,其中恶性病变34例,良性病变2例。CESM和DCE-MRI对乳腺癌检测的敏感性为100%。病灶大小无统计学差异,P=0.114。乳腺病变强化程度在CESM中显著低于DCE-MRI,P<0.01。两种检查方法均能检测出直径大小约3 mm的病变。CESM及DCE-MRI两种检查方法和病灶大小及强化程度进行的多分类有序logistic回归结果显示,CESM为c2=109.36,OR=0.331,P<0.001,DCE-MRI为c2=115.83,OR=0.232,P<0.001。结论 CESM具有较高的检测乳腺癌的灵敏度,具有较高的阳性预测值和较好的检查说服力,这对于乳腺癌的临床诊断和分期具有重要作用。Objective To retrospectively analyze the diagnostic performance of contrast-enhanced spectral mammography and dynamic contrast-enhanced magnetic resonance imaging in breast cancer.Methods A total of30patients with breast lesions underwent CESM and DCE-MRI examinations.Double blind and nonrandomized studies were used.Paired T test was used to analyze the size and enhanced intensity of the lesion.Sensitivity,accuracy,and positive predictive value were calculated.CESM and DCE-MRI with the size and enhanced intensity of the breast lesions were analyzed by multiple ordered logistic regressions.Results A total of34lesions were identified,including malignant lesions in34cases and benign lesions in2cases.The sensitivity of CESM and DCE-MRI in diagnosis of breast cancer was100%.There was no significant difference in lesion size,P=0.114.The degree of breast lesion enhancement in CESM was significantly lower than that of DCE-MRI,P<0.01.Two kinds of examination methods can detect the diameter of about3mm lesions.Multiple ordered logistic regression results of CESM and DCE-MRI with the lesion size and degree of enhancement in breast lesions showed that CESM c2=109.36,OR=0.331,P<0.001,DCE-MRI c2=115.83,OR=0.232,P<0.001.Conclusion CESM has high sensitivity,higher posttive predictive Value and better examination power in diagnosis of breast cancer,which plays an important role in clinical diagnosis and staging of breast cancer.

关 键 词：对比增强能谱乳腺X线摄影 动态对比增强 磁共振成像 乳腺癌 对比研究 

分 类 号：R814.41[医药卫生—影像医学与核医学]