抗阻运动对糖尿病前期伴轻度高血压人群血压的影响  

Effect of resistance exercise on blood pressure of people with mild hypertension in prediabetes

作　　者：麻晓君 戴霞[1] 罗祖纯 韦春[2] 陆丽荣 赵文飘 Xiao-jun Ma;Xia Dai;Zu-chun Luo;Chun Wei;Li-rong Lu;Wen-piao Zhao(The First Affiliated Hospital,Guangxi Medical University, Nanning, Guangxi 530021, China;Nursing College, Guangxi Medical University, Nanning, Guangxi 530021, China;The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning,Guangxi 530023, China)

机构地区：[1]广西医科大学第一附属医院,广西南宁530021 [2]广西医科大学护理学院,广西南宁530021 [3]广西中医药大学第一附属医院,广西南宁530023

出　　处：《中国现代医学杂志》2017年第28期45-50,共6页China Journal of Modern Medicine

基　　金：广西医疗卫生技术研究与开发课题项目(No:S201413_03);广西研究生教育创新计划项目(No:YCSZ2015111)

摘　　要：目的研究不同运动方式对社区糖尿病前期(IGR)人群血压的控制效果。方法于2015年6~8月在桂林的3个社区卫生服务中心长期管理的社区居民中筛选出符合标准的IGR合并轻度高血压人群83人,随机分为3组,经过1年的干预和随访,最终收集到67人的完整数据:抗阻运动组22人、有氧运动组23人、对照组22人。干预期间,对照组保持原有的生活方式,抗阻和有氧运动组分别进行相应的运动干预,约50 min/次,以集体形式隔天训练。对干预后3、6、12个月抽血查空腹血糖、空腹胰岛素和糖化血红蛋白(HbA1c),测血压,计算胰岛素抵抗指数(HOMA-IR)。结果 (1)不同时间点之间的HbA1c、HOMA-IR、收缩压(SBP)、舒张压(DBP)比较,差异有统计学意义(F=22.415、9.289、32.689和6.713,均P=0.000);3组间的HbA1c、HOMA-IR、SBP、DBP比较,差异有统计学意义(F=16.525、4.241、26.436和4.653,P=0.000、0.044、0.000和0.013),干预后抗阻运动组和有氧运动组的HbA1c、HOMA-IR、SBP、DBP低于对照组;3组的HbA1c、HOMA-IR、SBP、DBP变化趋势差异有统计学意义(F=19.134、4.782、22.520和6.792,均P=0.000),干预期间,对照组各指标总体呈上升趋势,两运动组各指标总体呈下降趋势,虽然两运动组不同时段各指标比较差异无统计学意义(P>0.05),但抗阻运动组的HbA1c、HOMAIR的下降幅度大于有氧运动组,且SBP、DBP下降幅度小于有氧运动组。(2)干预3个月时,有氧和抗阻运动组的HbA1c、HOMA-IR、DBP均低于干预前,有氧运动组SBP低于干预前;干预6个月时,有氧和抗阻运动组的HbA1c、SBP、DBP均低于干预前,抗阻运动组HOMA-IR低于干预前;干预12个月时,有氧和抗阻运动组的HbA1c、HOMA-IR、SBP、DBP均低于干预前,对照组HbA1c、SBP高于干预前,均差异有统计学意义(P<0.05)。结论抗阻和有氧运动均能安全有效地改善社区IGR合并轻度高血压人群的HbA1c、血压、HOMA-IR,值得推广。Objective To study the effect of different exercise methods on blood pressure(BP)control incommunity people with prediabetes.Methods In the period from June to August2015,the people who sufferedfrom prediabetes with mild hypertension(n=83)were selected from the community residents who had beenmanaged by three community health service centers in Guilin.The volunteers were randomly divided into3groups.After a year of intervention and follow-up,67people were eventually collected with22in the resistance exercisegroup,23in the aerobic exercise group and22in the control group.During the intervention period,the controlgroup maintained the original way of life;the resistance and aerobic exercise groups were given the correspondingexercise intervention,about50min each time,once every other day.In3,6and12months after intervention,fastingblood glucose,fasting insulin,glycosylated hemoglobin(HbA1c),BP and insulin resistance index(HOMA-IR)were measured.Results HbA1c,HOMA-IR,SBP and DBP at different time points were significantly different(F=22.415,9.289,32.689and6.713respectively;P=0.000).HbA1c,HOMA-IR,SBP and DBP were significantlydifferent among the three groups(F=16.525,4.241,26.436and4.653;P=0.000,0.044,0.000and0.013).Afterintervention,HbA1c,HOMA-IR,SBP and DBP of the resistance exercise group and the aerobic exercise group werelower than those of the control group;the change trends of HbA1c,HOMA-IR,SBP and DBP were significantlydifferent(F=19.134,4.782,22.520and6.792;P=0.000).During the intervention period,although the differenceswere not statistically significant between the two exercise groups when the index values of different time periods werecompared(P>0.05),the decline ranges of HbA1c and HOMA-IR in the resistance exercise group were greater thanthose in the aerobic exercise group,SBP and DBP of the aerobic exercise group decreased more obviously than thoseof the resistance exercise group.After3months,HbA1c,HOMA-IR and DBP of the aerobic group and the resistancegroup were lower than those before intervention;SBP of

关 键 词：抗阻运动 糖尿病前期 高血压 

分 类 号：R587.1[医药卫生—内分泌]