新生儿败血症临床特征和菌谱耐药分析  

Analysis of clinical features and bacterial spectrum drug-resistance in neonatal sepsis

作　　者：张惠[1] 叶青 ZHANG Hui;YE Qing(Department of Pediatrics, Yuyao People’s Hospital of Zhejiang Province, Yuyao 315400, China)

机构地区：[1]余姚市人民医院儿科,浙江余姚315400

出　　处：《中国生化药物杂志》2017年第11期377-378,共2页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨新生儿败血症临床特征及菌谱耐药特点。方法选择余姚市人民医院2010年1月～2015年12月收治的新生儿败血症200例，均行血培养，统计病原菌构成比，观察早发型、晚发型病原菌分布情况，并分析菌谱耐药率。结果共分离出病原菌200株，革兰阴性菌28株，占14.00%，以肺炎克雷伯杆菌、大肠埃希菌最为常见；革兰阳性菌172株，占86.00%，以金黄色葡萄球菌、表皮葡萄球菌最为多见。113株为早发型败血症病原菌，占56.5%；87株为晚发型败血症病原菌，占43.5%。结论通过分析新生儿败血症菌谱耐药特点，针对性对治疗用药进行选择，可最大程度改善预后。Objective To investigate the clinical features,bacterial spectrum drug-resistance of neonatal sepsis.Methods200cases of neonatal septicemia in Yuyao People's hospital of Zhejiang Province from January2010to December2015were treated by blood culture,counting the constituent ratio of pathogens,the early and late-onset pathogen bacteria distribution observation and drug-resistance rate of bacteria spectrum analysis.Results A total of200strains of bacteria were isolated,28strains of gram negative bacteria accounted for14.00%,with pulmonary Bauman Acinetobacter,Escherichia coli were the most common sterilization;172strains of gram positive bacteria accounted for86.00%,Staphylococcus aureus,Staphylococcus epidermidis were the most common.113strains were early-onset septicemia pathogens,accounting for56.5%;87were lateonset septicemia pathogens,accounting for43.5%.Conclusion Through the analysis of the characteristics of bacterial spectrum drug-resistance of neonatal sepsis,targeted treatment options,could maximize the prognosis.

关 键 词：新生儿败血症 菌谱分析 耐药率 

分 类 号：R722.131[医药卫生—儿科]