噻托溴铵配合整体护理对稳定期慢性阻塞性肺疾病的临床效果研究  

Study on the clinical efficacy of tiotropium bromide combined with holistic nursing on chronic obstructive pulmonary disease in its stationary phase

作　　者：唐敏婕 姜昕[2] 史宝欣 TANG Min-jie;JIANG Xin;SHI Bao-xin(School of Nursing,Tianjin Medical University, Tianjin 300070, China;Department of Traditional Chinese Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China;Hospice Care Research Center of Tianjin Medical University ,Tianjin 300070, China)

机构地区：[1]天津医科大学护理学院,天津300070 [2]天津医科大学总医院中医科,天津300052 [3]天津医科大学临终关怀研究中心,天津300070

出　　处：《中国生化药物杂志》2017年第12期88-90,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨噻托溴铵联合整体护理治疗稳定期慢性阻塞性肺疾病（COPD）的临床效果。方法选取天津医科大学总医院2015年5月~2016年5月收治的104例稳定期COPD患者，采用随机数字表法均分为2组。对照组予以噻托溴铵+常规护理治疗，观察组采取噻托溴铵+整体护理治疗。记录比较2组治疗效果。结果观察组治疗后总有效率为88.5%，高于对照组的69.2%（P＜0.05）。2组治疗后第1秒用力呼气容量（FEV1）、用力肺活量（FVC）、FEV1/FVC值较治疗前均升高（P＜0.01），且观察组以上指标升高更明显（P＜0.01）。观察组同期治疗后St.George呼吸问卷（SGRQ）评分低于对照组（P＜0.01），6min行走距离（6MWT）大于对照组（P＜0.01）。结论稳定期COPD应用噻托溴铵配合整体护理治疗更能有效缓解患者症状体征，改善肺功能，提高运动耐力和生活质量。Objective To investigate the clinical efficacy of tiotropium bromide combined with holistic nursing on chronic obstructive pulmonary disease(COPD)in the stationary phase.Methods The subjects of this study,104patients with COPD in its stationary phase admitted in our hospital from May2015to May2016,were evenly divided into two groups on the basis of random number table.The control group was treated with tiotropium bromide combined with conventional nursing,while the observation group the combination of tiotropium bromide and holistic nursing.Results The overall effective rate of the observation group after treatment was88.5%,much higher than69.2%of the control group(P<0.05).The forced expiratory volume at the first second(FEV1),forced vital capacity(FVC)and FEV1/FVC of both groups after treatment got remarkably increased as compared with those before treatment(P<0.01),and the improvement of the observation group in the above indicators was more significant(P<0.01).Compared with the control group,the observation group had much lower St.George’s respiratory questionnaire(SGRQ)score and higher6minute walking test(6MWT)value over the same period(P<0.01).Conclusion In treating COPD in its stationary phase the combination of tiotropium bromide and holistic nursing is more effective in reliving the symptoms in patients,improving their pulmonary function and exercise tolerance,and bettering their life,worth clinical promotion.

关 键 词：噻托溴铵 整体护理 稳定期 慢性阻塞性肺疾病 

分 类 号：R563[医药卫生—呼吸系统]