医用^(192)Ir放射源标称活度准确性的研究  

The study of the accuracies about the noted activity values of the medical radioactive sources ^(192)Ir

作　　者：刘宝喜 全红[1] 邱杰[2] 于浪[2] 杨波[2] 刘楠[2] 刘峡[2] 庞廷田[2] LIU Bao-xi;QUAN Hong;QIU Jie(School of Physics and Technology, Wuhan University, Wuhan 430072, China)

机构地区：[1]武汉大学物理科学与技术学院,湖北武汉430072 [2]中国医学科学院北京协和医学院协和医院放疗科,北京100730

出　　处：《中国医学装备》2017年第12期46-48,共3页China Medical Equipment

摘　　要：目的:比较进口医用铱192(^(192)Ir)放射源与国产^(192)Ir放射源标称活度的准确性。方法:回顾性分析北京协和医院放疗科自2006年至今近11年间2台后装机所使用的^(192)Ir放射源,其中医科达Nucletron后装机共使用荷兰进口源16枚,天津荣立后装机共使用北京原子高科公司提供的国产源19枚。在新投入临床使用前采用井形电离室进行实际源活度的测量,与标称活度进行比较。通过统计学软件SPSS19.0对进口源和国产源的测量结果进行分析。结果:国产源的测量偏差为(0.26±0.87)%,进口源的测量偏差为(1.1±1.3)%,进口源的活度偏差较大。对两组数据进行独立样本t检验,其结果表明,两种源间的差异有统计学意义(F=4.086,P<0.05)。结论:进口源和国产源的偏差均在临床可接受范围内,但对于活度偏差较大的放射源临床需考虑进行修正。进口源测量值与标称值的偏差值较大,投入临床使用前更需严格把控。Objective:To compare the accuracies about the noted activity values by the manufactories between the imported radioactive source and domestic radioactive source of medical192Ir.Methods:The radioactive sources of two afterloading devices,which one device was from Elekta Nucletron afterloading device(16imported radioactive sources)and other one was from Tianjin Rongli afterloading device(19imported radioactive sources),were researched by using retrospective analysis.Well-type ionization chamber was applied to measure actual activity before they were reused in clinical practice,and then the results were compared with the noted activity value by manufactories,respectively.The measurement results of imported and domestic sources were analyzed by means of statistical software SPSS19.0.Results:The activity deviation of imported source(1.1±1.3%)was significantly larger than that of domestic source(0.26±0.87%)as the independent samples T test(F=4.086,P<0.05).Conclusion:Although both of the two deviation values were in tolerance interval,the radioactive source of larger deviation should be thought to corrected in clinical practice.Therefore,imported radioactive source should be strictly detected and controlled before they were applied in clinical practice because there are larger deviation between the noted activity value and actual value in their radioactive sources.

关 键 词：铱192放射源 表观活度 井型电离室 后装治疗机 

分 类 号：R812[医药卫生—放射医学]