乳管内窥镜联合亚甲蓝双定位法诊断乳腺导管内瘤样病变及手术价值  

The diagnosis and surgery value of double localization method of mammary ductoscopy combined with methylene blue staining for tumor-like lesion in mammary duct

作　　者：刘恒[1] 王钢乐[1] 董懿[1] 纪楠[1] 曹技磊 LIU Heng;WANG Gang-yue;DONG Yi(Department of Breast Surgery, Beijing Obstetrics and Gynecology Hospital of Capital Medical University, Beijing 100006, China)

机构地区：[1]首都医科大学附属北京妇产医院乳腺科,北京100006

出　　处：《中国医学装备》2017年第12期89-92,共4页China Medical Equipment

摘　　要：目的:评估乳管内窥镜联合亚甲蓝染色双定位法对病理性乳头溢液患者导管内瘤样病变的诊断及手术治疗价值。方法:回顾性分析80例乳腺导管内瘤样病变患者术前经乳管内窥镜检查并联合亚甲蓝染色定位诊断结果,与术后病理结果进行对比,评价手术治疗效果。结果:乳管内窥镜下诊断导管内乳头状瘤与手术后病理诊断结果对比,其符合率为83.3%,乳腺癌诊断符合率为80%。良性病变与恶性病变在Ⅰ~Ⅲ级乳腺导管内的分布相比较,其差异有统计学意义(x2=30.026,P<0.05)。所有病例手术均定位准确,手术创面损伤小,随访至今未见复发。结论:乳管内窥镜联合亚甲蓝染色双定位法对乳腺导管内瘤样病变的诊断和手术治疗均有重要价值。Objective:To evaluate the diagnosis and curative value of double localizationmethod that mammary ductoscopy combined with methylene blue staining for tumorlikelesion in mammary duct of patients with pathological nipple discharge.Methods:Thedocuments of80patients with tumor-like lesion in mammary duct who underwent thedetection of double localization that mammary ductoscopy combined with methylene bluestaining before operation were researched by using retrospective analysis,and then the diagnostic results were compared with pathological results so as to evaluate the curative effect of surgery.Results:The coincidence rate of the diagnosis of intraductal papilloma between mammary ductoscopy and post-operative pathological results was83.3%,and the coincidence rate of breast carcinoma was80%.The differences of distributions of benign lesion and malignant lesion in mammary duct of I-III grade were significant(x2=30.026,P<0.05).Besides,all of operations were accuracy in localization,and the surface of wound were small,and the recurrent cases never been found since the start of follow-up.Conclusion:The double localization method that mammary ductoscopy combined with methylene blue staining has important value in the diagnosis and operative treatment.

关 键 词：乳头状瘤 乳管内窥镜 亚甲蓝染色 乳头溢液 

分 类 号：R655.8[医药卫生—外科学]