经皮冠状动脉介入术前后口服水化补液预防CIN效果观察  

Effect of oral hydration therapy in prevention of contrast induced nephropathy before and after percutaneous coronary intervention

作　　者：陶娟[1] 康立惠[1] 孙俊平[1] 张京梅[1] Tao Juan;Kang Lihui;Sun Junping;Zhang Jingmei(Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China)

机构地区：[1]首都医科大学附属北京安贞医院心内科15病房,北京100029

出　　处：《中国循证心血管医学杂志》2017年第11期1352-1353,1356,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的分析经皮冠状动脉介入治疗(PCI)术前、术后口服水化补液预防造影剂肾病(CIN)效果,并讨论其护理方法。方法连续选择2016年1月1日~2016年2月28日于首都医科大学附属北京安贞医院心内科进行冠状动脉介入治疗的不稳定性心绞痛患者156例,按照随机数字表法分为对照组(仅予以术后口服水化补液)和研究组(术前术后均予以口服水化补液),同时加强患者的临床护理,对比两组患者临床效果。结果研究组造影剂肾病发生率低于对照组造影剂肾病发生率,差异有统计学意义(2.4%vs.19.4%,χ~2=12.682,P<0.05),研究组患者造影剂肾病发生率、不良事件发生率均低于对照组(P<0.05);对照组患者不良反应的发生率为4.8%,研究组患者不良反应的发生率为27.8%,研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 PCI术前、术后口服水化补液并予以临床护理,可以降低造影剂肾病发生率,安全性高,效果良好。Objective To analyze the effect of oral hydration therapy in prevention of contrast induced nephropathy(CIN)before and after percutaneous coronary intervention(PCI),and discuss the nursing methods.Methods The patients(n=156)with unstable angina pectoris(UAP)undergone PCI were chosen from the Department of Cardiology in Beijing Anzhen Hospital affiliated to Capital University of Medical Sciences from Jan.1,2016to Feb.28,2016.All patients were divided,according to random digital table,into control group(given oral hydration therapy only after PCI)and study group(given oral hydration therapy before and after PCI).The clinical nursing was strengthened for patients and clinical efficacy was compared between2groups.Results The incidence of CIN was lower in study group than that in control group(2.4%vs.19.4%,χ2=12.682,P<0.05).The incidence of adverse events was4.8%in control group and27.8%in study group(P<0.05).Conclusion The oral hydration therapy and clinical nursing given to CIN patients before and after PCI can reduce the incidence of CIN with higher safety and better effect.

关 键 词：冠心病介入治疗 水化补液 造影剂肾病 

分 类 号：R816.2[医药卫生—放射医学]