PASS软件在观察性研究设计样本含量估算中的应用  

Application of PASS in the sample size estimation of the observational study design

作　　者：魏凤江[1,2] 胡良平 Wei Fengjiang;Hu Liangping(Department of Health Statistics, School of Public Health, Tianjin Medical University,Tianjin300070,China;Department of Genetics, College of Basic Medical Sciences, Tianjin Medical University, Tianjin300070, China;Consulting Center of Biomedical Statistics, Academy of Military Medical Sciences, Beijing100850, China;Specialty Committee of Clinical Scientific Research Statistics of World Federation of Chinese Medicine Societies, Beijing100029, China)

机构地区：[1]天津医科大学公共卫生学院卫生统计学教研室,天津300070 [2]天津医科大学基础医学院遗传学系,天津300070 [3]军事医学科学院生物医学统计学咨询中心,北京100850 [4]世界中医药学会联合会临床科研统计学专业委员会,北京100029

出　　处：《四川精神卫生》2017年第5期401-404,共4页Sichuan Mental Health

基　　金：国家高技术研究发展计划课题资助(2015AA020102)

摘　　要：样本含量估算是科研人员进行科研设计所关注的重要问题之一,合理估算样本含量是试验设计中的一个重要内容。本文应用PASS 11.0软件对临床研究中观察性研究(即队列研究、病例-对照研究和横断面研究)的样本含量进行计算。探讨PASS软件在科研过程中计算样本含量的实用性和准确性,为科研工作者在进行观察性研究设计阶段进行科学的样本含量估算提供参考。To estimate the sample size is one of the most important issues in the research design,and it is an important part of the experimental design to determine the sample size rationally.In this paper,we used PASS11.0software to calculate the sample size of the observational studies including cohort study,case-control study and cross-sectional study.In order to evaluate the practicability and accuracy of PASS software for the purpose of providing reference for the sample size estimation in the observational study design.

关 键 词：样本含量 队列研究 病例-对照研究 横断面研究 

分 类 号：R195.1[医药卫生—卫生统计学]