免疫性不孕(育)相关抗精子抗体的研究进展  

Research progress of antisperm antibody associated with immune infertility

作　　者：阴克强 双卫兵[1] YIN Ke-Qiang;SHUANG Wei-Bing(The First Hospital of Shanxi Medical University, Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院,山西太原030001

出　　处：《转化医学电子杂志》2017年第10期88-92,共5页E-Journal of Translational Medicine

基　　金：山西省高校2014年度131领军人才项目(晋教财【2015】41号165);山西医科大学第一医院中青年学科带头人资助项目(晋教科【2012】10号)

摘　　要：免疫性不孕(育)是引起不孕不育的主要原因之一,是指免疫系统激活后产生抗精子抗体(AsAb)并通过相关作用机制引起不孕不育.男性和女性均存在AsAb,其通过不同的作用机制干扰受精过程的各个阶段,从而导致不孕不育.本文就免疫性不孕(育)、精子抗原、AsAb及其作用机制、与AsAb相关的免疫因素、AsAb的检测、AsAb的治疗等方面进行综述.Immune infertility plays a major role in infertility,in which antispemi antibodies(A sA b)following immunological syetem,s activition result in infertility by different mechanisms.Immune infertility caused by AsAb,existed,in both male and female,is the result of interference of these antibodies in various stages of fertilization process.The article reviews immune infertility in male and female,sperm antigens,AsAb and its action mechanisms,immunological factors related to AsAb,detections and treatments of AsAb.

关 键 词：抗精子抗体 免疫性不孕(育) 精子抗原 

分 类 号：R711.6[医药卫生—妇产科学] R446.6[医药卫生—临床医学]