中药寡糖生物活性及炮制过程中化学反应研究概况  

Research Overview of Biological Activity and Chemical Reactions in Process of Oligosaccharides of TCM

作　　者：王佳 魏晓峰 任晓航 李祥溦 史辑[1,2,3] WANG Jia;WEI Xiao-feng;REN Xiao-hang;LI Xiang-wei;SHI Ji(School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;Key Laboratory of Analysis of Processing Principle, State Administration of Tradition Chinese Medicine,Dalian 116600, China;Liaoning Research Center of Traditional Chinese Medicine Processing Engineering, Dalian 116600, China)

机构地区：[1]辽宁中医药大学药学院,辽宁大连116600 [2]国家中医药管理局炮制原理解析重点实验室,辽宁大连116600 [3]辽宁省中药炮制工程技术研究中心,辽宁大连116600

出　　处：《中国中医药信息杂志》2018年第1期128-131,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(81473350);国家自然科学基金青年基金(81001635)

摘　　要：中药寡糖来源及分布广泛,以其特殊的生物活性和化学性质,在营养保健、疾病防治等方面有巨大潜力,其成分研究逐渐增多,并不断拓展研究及应用范围。中药寡糖可通过天然提取、降解和人工合成方法获取,其中以层析法为代表的天然提取方法最为适用。中药寡糖具有不同的基团和连接方式,其结构复杂,在炮制过程中也有不同化学反应。本文从中药寡糖的分离、生物活性及炮制过程中化学反应等方面综述该领域研究概况。The origin and distribution of oligosaccharides of TCM are extensive,and its special biological activity and chemical properties have great potential in health preserving and disease prevention and treatment.The researches about its components are increasing,and its research and application are expanded.Oligosaccharides of TCM can be obtained by natural extraction,degradation and artificial synthesis.Among them,the natural extraction method is the most suitable for chromatography.The oligosaccharides of TCM have different groups and connections,and the structure is complex,with different chemical reactions in the process.This article reviewed the research overview of oligosaccharides of TCM from the aspects of separation,biological activity and chemical reactions in the process.

关 键 词：寡糖 分离 生物活性 化学性质 综述 

分 类 号：R285.5[医药卫生—中药学] R283.1[医药卫生—中医学]