红花黄色素注射液对不稳定型心绞痛患者疗效及血液流变学的影响  

Efficacy of sailor yellow pigment injection on unstable angina and hemorheology

作　　者：石立鹏[1] 杜旭勤 李艳景 曹辉[1] 刘明怀 杨德钱 

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]重庆市垫江中医院,重庆408300

出　　处：《中医临床研究》2017年第32期17-19,共3页Clinical Journal Of Chinese Medicine

基　　金：国家科技惠民计划项目;项目名称:常见疾病适宜技术垫江县中医院示范基地建设;项目编号:2013GS500101-02;项目主持人:刘明怀;项目周期:2013年-2016年;全国基层名老中医专家传承工作室项目支持(国中医药办人教发[2015]25号)

摘　　要：目的:观察红花黄色素注射液对不稳定型心绞痛(UA)患者的临床疗效及血液流变学的影响。方法:将96例患者随机分为对照组和治疗组,各48例,对照组予以冠心病二级预防;治疗组在对照组的基础上加用红花黄色素注射液,疗程均为4周,观察治疗前后心绞痛症状、中医证候积分及血液流变学指标的改善情况。结果:治疗组心绞痛总有效率为89.58%,对照组心绞痛总有效率为66.67%,两组对比差异有统计学意义(P<0.05);治疗组中医证候积分总有效率为93.75%,对照组中医证候积分总有效率为79.17%,两组对比差异有统计学意义(P<0.05);两组血液流变学指标水平均较治疗前有所降低,组内比较差异有统计学意义(P<0.05),但治疗组下降更为显著,组间比较差异有统计学意义(P<0.05)。结论:红花黄色素注射液能够明显改善UA患者的临床症状,降低冠脉血液流变学指标,从而改善心肌缺血,有效缓解患者临床症状。Objective:To observe the efficacy of sailor yellow pigment injection on UA and hemorheology.Methods:96patients were randomly divided into the control group and treatment group,48cases in each.Both groups received standard treatment;the treatment group was given sailor yellow pigment injection more.Two groups were treated for4weeks.The angina pectoris,TCM syndrome and hemorheology were compared before and after treatment.Results:The efficiency of angina pectoris was89.58%in the treatment group and66.67%in the control group(P<0.05).Efficiency of TCM syndrome was93.75%in the treatment group and79.17%in the control group(P<0.05).The hemorheology was obviously reduced in two groups(P<0.05),that in the treatment group was lower than the control group(P<0.05).Conclusion:Sailor yellow pigment injection significantly improves the clinical symptoms of UA,reduces the hemorheology index,improves the myocardium ischemic,and significantly alleviates the clinical symptoms.

关 键 词：红花黄色素 不稳定型心绞痛 临床疗效 血液流变学 临床观察 

分 类 号：R541.4[医药卫生—心血管疾病]