仔猪肠道微生物研究进展  

Current understanding of the intestinal microbiota of piglets

作　　者：夏耀耀 任文凯[1,2] 黄瑞林 曾本华[3] 魏泓[3] 印遇龙[1] XIA Yao-yao;REN Wen-kai;HUANG Rui-lin;ZENG Ben-hua;WEI Hong;YIN Yu-long(Key Laboratory of Agro - Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observation a;University of Chinese Academy of Sciences, Beijing100049;Department of Laboratory Animal Science, College of Basic Medicine Science,Third Military Medical University, Chongqing400038)

机构地区：[1]中国科学院亚热带农业生态研究所畜禽健康养殖研究中心,中国科学院亚热带农业生态过程重点实验室,畜禽养殖污染控制与资源化技术国家工程实验室,湖南省畜禽健康养殖工程技术研究中心,农业部中南动物营养与饲料科学观测实验站,长沙410125 [2]中国科学院大学,北京100049 [3]第三军医大学基础部实验动物学教研室,重庆400038

出　　处：《中国实验动物学报》2017年第6期681-688,共8页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家自然科学基金(No.31330075,No.31301989)

摘　　要：肠道菌群在哺乳动物及人类健康的作用正日益受到重视。仔猪的健康生长需要一个动态平衡的肠道微生态环境。然而,在猪的生命周期中,从食管到直肠的微生物分布与组成存在时间和空间的变化。健康的肠道菌群具有促进猪的营养代谢,维持肠黏膜屏障,调节免疫应答,抑制病原菌感染等功能。多种因素对猪肠道菌群的形成与稳定具有重要的作用,包括分娩方式(经过产道或剖宫产)、幼龄时期饮食(母乳或配方饲料)、抗生素或抗生素样分子的使用等。本文主要从仔猪肠道微生物组成与定植、功能、影响肠道微生物的因素等方面论述了仔猪肠道微生物与仔猪肠道健康的关系,从而加深肠道微生物对维护仔猪肠道健康作用的认识。he role of intestinal microbiota in mammals and humans are gaining increasing attention.The health of piglets requires a dynamically balanced intestinal microbiota.However,there are temporal and spatial changes in the distribution and composition of microbiota from the esophagus to the rectum during the life cycle of the pig.The intestinal microbiota has various beneficial functions in pig,like nutrient metabolism,intestinal mucosal barrier,immune responses and pathogen infection.A variety of factors play an important role in the formation and stabilization of intestinal microbiota,including the ways of delivery(vaginal or caesarean),the diet during infancy(breast milk or formula feeds)and the usage of antibiotics or antibiotic-like molecules.In this review,we mainly discussed the relationship between intestinal microbiota and the intestinal health of piglets from the aspects of the composition and colonization of intestinal microbiota,as well as the functions and influencing factors of intestinal microbiota,so as to further understanding the importance of intestinal microbiota in intestinal function of piglets.

关 键 词：肠道微生物菌群 肠道健康 仔猪 

分 类 号：Q95-33[生物学—动物学]