光照对大脑功能的影响研究进展  

Research Progress of the Effect on Brain Function by Light

作　　者：孙芳玲[1,2] 郭德玉 王文[1,2] SUN Fangling;GUO Deyu;WANG Wen(Xuwu Hospital Capital Medical University,Beijing 100053, China;Beijing Municipal Geriatric Medical Research Centre,Beijing 100053, China)

机构地区：[1]首都医科大学宣武医院,北京100053 [2]北京市老年病医疗研究中心,北京100053

出　　处：《照明工程学报》2017年第6期16-19,共4页China Illuminating Engineering Journal

基　　金：国家自然科学基金项目(81503049;81373994;81573633)

摘　　要：光照是影响生物钟节律重要的因素之一。光照条件的变化通过视觉通路向大脑中的生物钟结构发送信号进而调整生理和行为的节律。同时,光照还可以通过非视觉通路影响大脑功能和认知能力等。本文对光照对生物钟节律的调控以及对大脑功能的影响的研究进展进行综述,希望为光生物安全研究、环境光照设计以及相关疾病的临床治疗提供参考依据。Light is one of the important regulators of the circadian clock.Light provides visual information to clock systems in brain and guides physiological rhythms and behavior.And light also exerts non-visual effects on brain functions such as sleep/wake regulation and cognition.In this review,we provide an overview of the physiological basis of light as they emerged from circadian rhythm research,and summarize recent data that reveal the effects of light on brain function,in order to provide insights for lighting design,photobiological safety study and clinical therapy of related diseases.

关 键 词：光照 昼夜节律 生物钟 大脑功能 

分 类 号：Q42[生物学—神经生物学]