感染防控助推抗菌药物合理应用  

Improving rational use of antimicrobial agents by infection prevention and control

作　　者：赵艳春[1] 贾建侠[1] 任军红[1] 赵秀莉[1] 贾会学[1] 姚希[1] 马凌悦[1] 周颖[1] 李六亿[1] 潘义生[1] ZHAO Yan-chun;JIA Jian-xia;REN Jun-hong;ZHAO Xiu-li;JIA Hui-xue;YAO Xi;MA Ling-yue;ZHOU Ying;LI Liu-yi;PAN Yi-sheng(Peking University First Hospital, Beijing 100034, China)

机构地区：[1]北京大学第一医院,北京100034

出　　处：《中国感染控制杂志》2018年第1期60-62,共3页Chinese Journal of Infection Control

基　　金：中国医院协会医院感染预防与控制能力建设项目基金(CHA-2012-XSPX-0629-1)

摘　　要：目的评价采取感染防控措施对管理抗菌药物合理应用的效果。方法选取某院2011—2015年住院患者为研究对象,采取一系列感染防控干预措施,评价干预效果。结果实施综合干预措施后,手卫生依从率逐年提升,从2011年的38.17%提高至2015年的87.16%,差异有统计学意义(χ~2=48.50,P<0.05)。医院感染发生率由1.45%下降至1.06%,差异有统计学意义(χ~2=42.50,P<0.05);2011—2015年医院抗菌药物使用强度分别为63.1、44.4、40.0、40.8、40.5,呈逐年下降趋势。结论采取有效的感染防控措施对推进抗菌药物合理应用管理具有明显效果,有利于降低抗菌药物的临床使用强度。ObjectiveTo evaluate the efficacy of infection prevention and control measures on the management of rational use of antimicrobial agents.MethodsPatients who were admitted in a hospital from2011to2015were as the research object,a series of infection prevention and control intervention measure were taken,efficacy of intervention measures were evaluated.ResultsAfter the implementation of comprehensive intervention measures,compliance rate of hand hygiene increased year by year,from38.17%in2011to87.16%in2015,difference was statistically significant(χ2=48.50,P<0.05).Incidence of healthcare associated infection dropped from1.45%to1.06%,difference was statistically significant(χ2=42.50,P<0.05);antimicrobial use density in2011-2015were63.1,44.4,40.0,40.8,and40.5respectively,which showed a decreasing tendency.ConclusionEffective infection prevention and control measures have obvious effect on promoting management of rational use of antimicrobial agents,it is helpful for reducing the clinical use density of antimicrobial agents.

关 键 词：医院感染 抗菌药物 合理使用 干预效果 

分 类 号：R181.32[医药卫生—流行病学]