石英晶体微天平研究刷状聚合物的自组装过程  

A Study of Preparing Self-assembly Brush Polymer by Quartz Crystal Microbalance

作　　者：刘卅[1,2] 钟春婷 王卫卫 王艳艳[1,2] 任力 Liu Sa;Zhong Chun-ting;Wang Wei-wei;Wang Yan-yan;Ren Li(School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China;National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China)

机构地区：[1]华南理工大学材料科学与工程学院,广东广州510640 [2]华南理工大学,国家人体组织功能重建工程技术研究中心,广东广州510006

出　　处：《广东工业大学学报》2018年第2期1-5,共5页Journal of Guangdong University of Technology

基　　金：国家重点研发计划项目(2017YFC1103402);国家自然科学基金资助项目(51673071);广东省自然科学基金资助项目(2016A030313509);广东省科技计划项目(2016B090918040,2014B090907004)

摘　　要：利用石英晶体微天平研究β-环糊精修饰的壳聚糖与金刚烷甲酸聚乙二醇单甲醚酯进行主客体自组装的过程,从而制备刷状聚合物.结果显示:吸附初期,ΔF明显下降而ΔD显著上升,随后两者变化都不大,逐渐达到平衡,向样品池通入去离子水,ΔF稍微上升而ΔD稍微下降.这表明,在自组装过程中,β-环糊精与金刚烷发生包结络合作用,存在两个动力学过程,界面上吸附的高分子链发生了构象变化.这一工作为研究固/液界面的主客体自组装反应过程提供了新的途径.The host-guest self-assembly process betweenβ-cyclodextrin modified chitosan(the host polymer)and methoxypoly(ethylene glycol)adamantane carboxylate(the guest polymer)was studied by quartz crystal microbalance,which further prepared brush polymer.Quartz crystal surface,which was coated,was placed in the sample cell for testing.After the baseline was balanced,solution was passed into the sample cell.At the same time,the change inΔF andΔD as a function of time was recorded.Results indicated thatΔF decreased andΔD increased significantly in the initial stage,and they both changed slowly and gradually reached equilibrium.When deionized water was passed into the sample cell,ΔF increased andΔD decreased slightly until balance was reached.This information demonstrated the host-guest self-assembly betweenβ-cyclodextrin and adamantane and this process showed two dynamic procedures coupled with chain conformational changes of polymer.This work may provide a new method for the research of the host-guest self-assembly process on solid/liquid interface.

关 键 词：主客体自组装 石英晶体微天平 固/液界面 构象变化 刷状聚合物 

分 类 号：R318.021[医药卫生—生物医学工程] R322.73[医药卫生—基础医学]