层层自组装制备Fe_3O_4@SiO_2@CdSe/CdS磁性荧光双功能材料  

Preparation of bifuntional magnetic fluorescent composite Fe_3O_4@SiO_2@CdSe/CdS by layer-by-layer self-assembly technique

作　　者：王胜男 王秀玲 董淑玲 刘勇健 翁婷 WANG Shengnan;WANG Xiuling;DONG Shuling;LIU Yongjian;WENG Ting(School of Chemistry,Biology and Material Engineering,SUST,Suzhou 215009,China;Jiangsu Key Laboratory of Environmental Functional Material,Suzhou 215009,China)

机构地区：[1]苏州科技大学化学生物与材料工程学院,江苏苏州215009 [2]江苏省环境功能材料重点实验室,江苏苏州215009

出　　处：《苏州科技大学学报（自然科学版）》2018年第1期44-49,共6页Journal of Suzhou University of Science and Technology（Natural Science Edition）

基　　金：国家自然科学基金资助项目(51103120)

摘　　要：以化学共沉淀法制备Fe_3O_4磁性纳米颗粒,通过stober水解法对其进行表面改性,制备出核壳结构的二氧化硅磁性微球,采用层层自组装技术将聚二烯丙基二甲基氯化铵(PDDA)修饰到微球表面。将该微球与巯基乙酸修饰后的CdSe/CdS量子点连接,得到Fe_3O_4@SiO_2@CdSe/CdS磁性荧光双功能复合微球。通过傅立叶变换红外光谱仪(FTIR)、X射线衍射(XRD)、振动样品磁强计(VSM)、透射电子显微镜(TEM)、荧光分光光度计、荧光显微镜等对该复合微球进行结构的表征以及性能的测试。结果表明,制备的复合材料磁强度高、分散性好、荧光性能优异,有望在细胞分离、靶向治疗、荧光标记等生命科学领域得到广泛的应用。Fe3O4magnetic nanoparticles were prepared by chemical coprecipitation method.The Fe3O4were modified by stober hydrolysis method to prepare core-shell silica magnetic microspheres.Then the microspheres were modified with polydiallyldimethyl(PDDA)by layer-by-layer self-assembly technique.The CdSe/CdS quantum dots were modified with thioglycolic acid,and connected to magnetic microspheres.Finally,Fe3O4@SiO2@CdSe/CdS magnetic fluorescent bifunctional composite microspheres were prepared successfully.The composite microspheres were characterized and tested by Fourier transform infrared spectroscopy(FTIR),X-ray diffraction(XRD),Vibrating sample magnetometer(VSM),Transmission electron microscopy(TEM),fluorescence spectrophotometer and fluorescence microscope.The results show that the prepared composites have high magnetic intensity,good dispersity and excellent fluorescence property.It is expected to be widely used in the fields of life sciences,such as cell separation,targeting therapy,fluorescence labeling and so on.

关 键 词：Fe3O4磁性纳米颗粒 二氧化硅 层层自组装 量子点 双功能复合材料 

分 类 号：TQ174[化学工程—陶瓷工业]