急性心肌梗死患者病程与心率减速力的相关性研究  

Correlation between Duration of Heart Disease and Deceleration in Patients with Acute Myocardial Infarction

作　　者：宋旷蓉[1] 卢佳佳[1] 邓宇英[1] 张硕[1] 赵良桥[1] 黄汉钦[1] 高婵 冷永群[1] SONG Kuang-rong;LU Jia-jia;DENG Yu-ying;ZHANG Shuo;ZHAO Liang-qiao;HUANG Han-qin;GAO Chan;LENG Yong-qun(Department of ECG Diagnosis,Wuhan No.1 Hospital,Wuhan 430030,China)

机构地区：[1]武汉市第一医院心电诊断科,湖北省武汉市430030

出　　处：《中国全科医学》2018年第7期809-812,共4页Chinese General Practice

基　　金：2015年度武汉市卫计委基金(WX15B19)--关于不同静息心率的原发性高血压病发生发展中自主神经变化规律的研究

摘　　要：目的探讨急性心肌梗死(AMI)患者病程与心率减速力的相关性。方法选取2011年1月—2015年5月在武汉市第一医院接受治疗的AMI患者91例,根据病程将其分为:A组(病程<1个月,n=28),B组(病程为1~3个月,n=31),C组(病程为4~6个月,n=16),D组(病程>6个月,n=16);另选取同期在本院接受体检的健康者92例,为对照组。比较5组心率减速力(DC)以及连续心率减速力(DRs)中的DR2、DR4、DR8。采用Spearman秩相关分析AMI患者病程与DC、DRs的相关性。结果 5组DC及DR2、DR4、DR8水平比较,差异有统计学意义(P<0.05)。DC、DR4、DR8与AMI患者病程呈正相关(r_s值分别为0.546、0.614、0.324,P<0.05),DR2与AMI患者病程无相关关系(r_s=0.088,P>0.05)。结论 AMI患者病程越短,DC值较低,迷走神经功能活性降低,猝死风险越高。Objective To investigate the regularity of changes in deceleration capacity(DC)of heart rate in patients with different duration of acute myocardial infarction(AMI).Methods The enrolled participants were all from Wuhan No.1 Hospital,including 91 cases of AMI(AMI group)receiving treatment from January 2011 to May 2015 and 92 healthy controls(control group)underwent physical examination during the same period.Based on the duration of AMI,AMI patients were divided into subgroup A(<1 month,n=28),subgroup B(1-3 months,n=31),subgroup C(4-6 months,n=16),and subgroup D(>6 months,n=16).The DC and DR2,DR4 and DR8 these three consecutive heart rate deceleration runs(DRs)were compared between the groups.Spearman correlation analysis was performed to investigate the correlation beteween different duration of AMI and DC,DR.Results The value of DC and DRs,as well as DRs of cycles differed significantly between the controls and four AMI subgroups(P<0.05).The value of DC,DR4 and DR8 increased with the prolongation of the duration of AMI(rs=0.546,0.614,0.324,P<0.05).The value of DR2 did not correlate with the duration of AMI(rs=0.088,P>0.05).Conclusion The value of DC decreased with the duration of AMI,leading to decreased activity of the vagus nerve and the higher the risk of sudden death.

关 键 词：心肌梗死 心率减速力 病程 

分 类 号：R542.22[医药卫生—心血管疾病]