慢性阻塞性肺病急性加重患者预后影响因素分析  

Analysis of Prognostic Influencing Factors in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

作　　者：刘延一[1] 杨俊华[1] 叶丹[2] 曾凤梅 刘玉苗[1] 雷虹[1] 张菊[1] Liu Yanyi;Yang Junhua;Ye Dan;Zeng Fengmei;Liu Yumiao;Lei Hong;Zhang Ju(Department of Nosocomial Infection Management,The First People's Hospital of Longquanyi District,Chengdu 610100,China;Department of Clinical Laboratory,The First People's Hospital of Longquanyi District,Chengdu 610100,China)

机构地区：[1]成都市龙泉驿区第一人民医院院感科,成都610100 [2]成都市龙泉驿区第一人民医院检验科,成都610100

出　　处：《成都医学院学报》2018年第1期81-84,88,共5页Journal of Chengdu Medical College

基　　金：四川省预防医学会医院感染预防与控制研究基金(No:SCGK006);成都市卫生和计划生育委员会科研课题(No:2015057)

摘　　要：目的探讨影响慢性阻塞性肺病急性加重(AECOPD)患者预后的相关因素,为制定AECOPD防控策略提供依据。方法选取2015年1月至2017年3月成都市龙泉驿区第一人民医院收治的AECOPD合并肺部细菌感染患者77例(感染组)与同期未合并肺部细菌感染患者44例(非感染组)作为研究对象,比较两组患者6个月后再住院次数,并采用单因素及多因素Logistic回归对AECOPD合并肺部细菌感染患者再住院的易感因素进行分析。结果感染组患者出院后6个月内再入院率为53.25%,非感染组患者再住院率为34.09%,差异有统计学意义(P<0.05)。单因素及多因素Logistic回归分析结果显示,住院时长、既往1年因本病住院次数是AECOPD合并肺部细菌感染患者再次住院的独立危险因素(P<0.05)。结论合并肺部细菌感染是AECOPD患者发生再次住院的重要原因,住院时长、既往1年因本病住院次数是AECOPD合并肺部细菌感染患者发生再次住院的危险因素,提早对这些危险因素进行预防控制,可减少AECOPD肺部感染患者再次住院次数。Objective To investigate the prognostic influencing factors of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and provide the scientific evidence for prevention and control of AECOPD.Methods 77 patients with AECOPD complicated with respiratory tract bacterial infections(RTBI)treated in The First People's Hospital of Longquanyi District from January of 2015 to March of 2017 were selected and classified into the infection group,while the other AECOPD patients without RTBI over the corresponding period were selected and classified into the non-infection group.The times of rehospitalization within half a year were compared between the two groups,and the univariate analysis and the multivariate logistic regression analysis were performed to analyze the predisposing factors for rehospitalization in patients with AECOPD complicated with RTBI.Results The rehospitalization rate within 6 months after discharge was 53.2%in the infection group and 34.1%in the non-infection group,and the difference was statistically significant(P<0.05).The results of the single and multiple factor analysis showed that the length of hospitalization and the times of hospitalization for AECOPD in the past year are the independent risk factors for rehospitalization in patients with AECOPD complicated with RTBI(P<0.05).Conclusion Being complicated with RTBI is one of the important reason for the rehospitalization incidence in AECOPD patients.The length of hospitalization and the times of hospitalization for AECOPD in the past year are the independent risk factors for rehospitalization in patients with AECOPD complicated with RTBI.The early prevention and control of these risk factors can reduce the times of rehospitalization in patients with AECOPD complicated with RTBI.

关 键 词：慢性阻塞性肺疾病 急性加重 AECOPD 再住院 感染 影响因素 

分 类 号：R563[医药卫生—呼吸系统]