斑点追踪分层应变技术评价晚发型重度子痫前期患者的左室收缩功能  

Evaluation of left ventricular systolic function in patients with late-onset severe preeclampsia by layer-specific speckle-tracking

作　　者：谢彩霞[1] 白雪[1] 李爱明[1] 范淑静[1] 拓胜军[2] XIE Caixia;BAI Xue;LI Aiming;FAN Shujing;TA Shengjun(Department of Third ward of Obstetrics and Gynecology,Shaanxi 716000,China;the People’s Hospital of Yan’an,Shaanxi 716000,China)

机构地区：[1]陕西省延安市人民医院妇产科三病区,716000 [2]陕西省延安市人民医院超声诊断科,716000

出　　处：《临床超声医学杂志》2018年第3期153-156,共4页Journal of Clinical Ultrasound in Medicine

基　　金：延安市科技计划项目(2016HM-04-03)

摘　　要：目的应用斑点追踪分层应变技术评估晚发型重度子痫前期(LO-SPE)患者左室各层收缩功能的早期变化情况。方法选取无症状和左室射血分数正常的LO-SPE患者51例(LO-SPE组),以及同期年龄和孕龄与之匹配的正常孕妇52例(晚孕健康对照组)和非孕健康妇女50例(非孕健康对照组)。采用纵向分层应变技术测量所有受试者左室纵向心内膜应变(GLSendo)、纵向中层应变(GLSmid)及纵向心外膜应变(GLSepi),并获取晚孕受试者产后3个月的应变数据,比较三组间各参数变化。结果晚孕健康对照组产前GLSendo、GLSmid及GLSepi均较非孕健康对照组减低(均P<0.05),产后显著恢复并达到非孕健康对照组水平。LO-SPE组产前GLSendo、GLSmid及GLSepi均较晚孕健康对照组及非孕健康对照组减低(均P<0.05),产后GLSendo和GLSmid均较产前显著恢复(均P<0.05),且达到非孕健康对照组水平;GLSendo于产后虽较术前显著恢复(P<0.05),但与非孕健康对照组比较差异仍有统计学意义(P<0.05)。结论斑点追踪分层应变技术在评估LO-SPE患者左室早期心肌损害方面具有一定价值。Objective To explore the value of layer-specific speckle-tracking on assessing the early changes of left ventricular(LV)systolic function in patients with late-onset severe preeclampsia(LO-SPE).Methods A total of51patients with LO-SPE of asymptomatic and left ventricular ejection fraction(LVEF)well-preserved(LO-SPE group),52age-,gestational age-matched normal pregnancy women(NP group)and50age-matched non-pregnant women as control group were included.Longitudinal strains of the LV endocardium,myocardium,and epicardium(GLSendo,GLSmid and GLSepi)were obtained by longitudinal layer-specific strain technology,the parameters were also obtained from normal late-pregnant women of3months postpartum,the data were compared among three groups.Results Compared with the control group,GLSendo,GLSmid and GLSepi were significantly decreased in NP group(all P<0.05),and subsequently returned to the normal level after delivery.GLSendo,GLSmid and GLSepi were significantly reduced in LO-SPE group compared with NP group and control group,and GLSendo,GLSmid were improved dramatically after delivery(all P<0.05),even returned to the level of NP group.Although GLSendo was increased obviously,there was significant difference compared with the control group(P<0.05).Conclusion Layer-specific speckle-tracking has a certain value in evaluating early impairment of LV in patients with LO-SPE.

关 键 词：斑点追踪成像 纵向分层 应变 重度子痫前期 晚发型 收缩功能 心室 左 

分 类 号：R540.45[医药卫生—心血管疾病]