中药材有效部位总黄酮含量测定方法研究概述  

Research Overview on Content Determination Methods of Total Flavonoids in Effective Parts of Chinese Materia Medica

作　　者：包强[1] 刘丽梅[2] 王延玲 毕映燕[1] BAO Qiang;LIU Li-mei;WANG Yan-ling;BI Ying-yan(Gansu Provincial Hospital of TCM, Lanzhou 730050, China;Institute of Basic Theory Research of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China)

机构地区：[1]甘肃省中医院,甘肃兰州730050 [2]中国中医科学院中医基础理论研究所,北京100700

出　　处：《中国中医药信息杂志》2018年第4期136-140,共5页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：中国中医科学院基本科研业务费自主选题项目(YZ-1438)

摘　　要：黄酮类化合物为多种中药材有效成分,具有广泛的生物活性和临床应用范围,其种类繁多、成分复杂,仅对某种或若干有效/指标性成分进行定量分析未必能反映其总黄酮量,存在一定局限性。而测定有效部位总黄酮含量是中药材及中药制剂质量控制的重要内容。目前,总黄酮含量测定方法主要有紫外-可见分光光度法、荧光分光光度法、高效液相色谱法、毛细管电泳法、薄层色谱法及近红外光谱法等。本文对中药材总黄酮含量测定方法及特点进行综述,为中药材质量控制提供参考。The flavonoids are the active ingredients of many Chinese materia medica,with widespread biological activities and a wide range of clinical application.There are many types of flavonoids,and its chemical structure is complex.Quantitative analysis of only one or several valid/indexed components may not necessarily reflect the amount of total flavonoids,with some limitations.The content determination of total flavonoids in effective parts of Chinese materia medica is an important aspect of quality control.The main methods for determining total flavonoid content are as follows:UV-visible spectropho-tometry,fluorescence spectrophotometry,high performance liquid chromatography,capillary electrophoresis,thin layer chromatography,as well as near-infrared spectroscopy and so on.In this article,the methods and characteristics in the determination of total flavonoids in Chinese materia medica were reviewed,so as to provide references for the quality control of Chinese materia medica.

关 键 词：总黄酮 中药材 含量测定 综述 

分 类 号：R284[医药卫生—中药学]