院内鲍曼不动杆菌感染患者预后危险因素分析  

Hospital's analysis on prognostic risk factors affecting acquired acinetobacter baumannii infected patients

作　　者：旷南岳[1] 漆新文[1] 李文军[1] KUANG Nanyue;QI Xinwen;LI Wenjun(Department of Pharmacy,Hospital of Xinjiang Production and Construction Crops,Urumqi,Xinjiang 830001,China)

机构地区：[1]新疆生产建设兵团医院药学部,新疆乌鲁木齐830001

出　　处：《安徽医药》2018年第4期789-792,共4页Anhui Medical and Pharmaceutical Journal

基　　金：新疆兵团科技计划项目(2015AB034)

摘　　要：目的探讨院内鲍曼不动杆菌(AB)感染患者的预后危险因素。方法回顾性分析141例院内AB感染患者的病例资料,以随访患者确诊为AB感染后60 d临床结局为依据分为死亡组(53例)和存活组(88例),同时收集患者的相关临床病例资料,通过COX回归分析确定影响AB感染患者的预后独立危险因素。结果单因素分析得出AB感染患者的预后危险因素包括:年龄、是否入住ICU、长期卧床、胃管、碳青霉烯类使用、糖肽类使用、合并革兰阳性(G+)菌感染、合并革兰阴性(G-)菌感染、器官功能不全、急性生理与慢性健康评分(APACHE-Ⅱ)差值和序贯性脏器衰竭评价评分(SOFA)差值;多因素分析得出碳青霉烯类使用、合并G-菌感染、器官功能不全和APACHE-Ⅱ评分差值是AB感染患者预后的独立危险因素。结论院内AB感染患者预后的独立危险因素为碳青霉烯类使用、合并G-菌感染、器官功能不全和APACHE-Ⅱ评分差值。Objective Study of analysis on prognostic risk factors affecting Acinetobacter baumannii(AB)infected patients.MethodsBy retrospective analysis on141cases of acquired AB infected patients in a general3A hospital during from January of2015to December of2016,based on the clinical outcomes of60d after the follow-up patients diagnosed as the AB infected,they were separated to the deceased group(53cases)and survived group(88cases),and collected relevant clinical documents of them.Through COX regression analysis,to determine the prognostic risk independent factors affecting AB infected patients.Results The single-factor analysis showed that the prognostic risk factors of AB infected patients embrace:age,whether having stayed in ICU,long-term bed,stomach tube,taking Carbopenems,using glycopeptides,Gram positive,Gram negative,organ dysfunction,APACHE-Ⅱscore difference and SOFA score difference.The multi-factor analysis indicated that taking Carbopenems,Gram positive infection,organ dysfunction,APACHE-ⅡCscore difference were the prognostic independent risk factors influencing AB infected patients.Conclusions The independent risk factors,having impact on death of hospital acquired AB infected patients,embrace taking Carbopenems,Gram positive infection,organ dysfunction and APACHE-Ⅱscore difference.

关 键 词：鲍曼不动杆菌 危险因素 预后因素 

分 类 号：R516[医药卫生—内科学]