不同剂量微波治疗对骨折术后钛合金植入物毗邻组织的影响（英文）  

Effects of different doses of microwave therapy on adjacent tissue of titanium alloy implants after fracture surgery

作　　者：王刚[1] 徐义明[1] 叶冬梅[1] 付腾飞[1] 邹玉珍[1] 冯宪煊[1] 白跃宏[1] Wang Gang;Xu Yi-ming;Ye Dong-mei;Fu Teng-fei;Zou Yu-zhen;Feng Xian-xuan;Bai Yue-hong(Department of Rehabilitation,Affiliated Sixth People’s Hospital of Shanghai Jiao Tong University,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院康复医学科,上海市200233

出　　处：《中国组织工程研究》2018年第7期1072-1077,共6页Chinese Journal of Tissue Engineering Research

基　　金：the Scientific Research Program of Science and Technology Commission of Shanghai City,No.13231202600~~

摘　　要：背景:微波治疗是临床常用的康复物理治疗方法,具有温热效应,能够促进治疗部位血液循环,可被用来促进损伤的骨组织恢复。通常,金属植入物被列为微波治疗的禁忌证。目的:观察微波治疗下钛合金植入物周围组织的热损伤情况。方法:将44只新西兰白兔随机分为植入物组和对照组。植入物组构建新西兰白兔股骨中段骨折动物模型,对骨折模型处给予钛合金内固定系统固定。对照组仅造模。2组在术后3 d开始对白兔股骨中段骨折处行连续30 d的2 450 MHz微波治疗,剂量为20 W或40 W,每天治疗20 min。结果与结论:植入物组和对照组经20 W的微波干预后,植入物毗邻组织温度没有明显上升,且没有出现严重组织热损伤;而经40 W的微波干预后,植入物毗邻组织温度明显上升,且40 W植入物组植入物毗邻组织损伤明显。结果提示低剂量的微波治疗可用于治疗骨折钛合金植入物固定术后的康复治疗。BACKGROUND:Microwave treatment is a common physical therapy method that can increase the temperature and blood circulation of deep tissues,and is used for improving fracture repair.However,microwave treatment cannot be used if there is surgically implanted metal plate or screw.OBJECTIVE:To observe the dame of microwave treatment to the tissues surrounding the titanium alloy implants.METHODS:Forty-four New Zealand white rabbits were randomized into experimental and control groups.The model of the fracture at the middle of the femur was established in all rabbits,and the rabbits in the experimental group were implanted with titanium alloy internal fixation systems.A 30-day microwave treatment(2 450 MHz,20 W or 40 W,20 minutes daily)was applied to the fracture site in all rabbits at 3 days after operation.RESULTS AND CONCLUSION:After 20 W of wave microwave treatment,the temperature of tissues around the implants showed no significant increase or severe heat injury.While,40 W of wave microwave treatment significantly increased the temperature of tissues around the implants and the tissue was damaged severely.Our results indicate that,the low-dosage microwave treatment may be a promising method in the rehabilitation therapy of fractures with titanium alloy internal fixation.

关 键 词：微波 假体和植入物 钛 组织工程 

分 类 号：R318[医药卫生—生物医学工程]