检测抗风湿类中成药和保健品非法添加化学药物的研究进展  

Research advances on analytical technologies of illegally adulterated chemical substances in antirheumatic Chinese patent medicines and health foods

作　　者：徐硕[1] 金鹏飞[1] 何笑荣[1] 徐文峰[1] 邝咏梅[1] XU Shuo;JIN Pengfei;HE Xiaorong;XU Wenfeng;KUANG Yongmei(Department of Pharmaceutical Science,Beijing Hospital,National Center of Gerontology,Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation,Beijing 100730,China)

机构地区：[1]北京医院药学部,国家老年医学中心,药物临床风险与个体化应用评价北京市重点实验室,北京100730

出　　处：《西北药学杂志》2018年第1期133-136,共4页Northwest Pharmaceutical Journal

基　　金：北京医院科技新星项目(编号:BJ-2016-039)

摘　　要：目的了解抗风湿类中成药和保健品中非法添加化学药物检测技术的进展。方法通过查阅相关文献和归纳总结,对近年来检测抗风湿类中成药和保健品中非法添加化学药物技术的文献进行综述。结果抗风湿类中成药和保健品中非法添加的化学药物主要包括糖皮质激素类、非甾体类抗炎药、镇痛药和抗生素类。检测方法包括TLC、HPLC、HPLC-MS/MS和UPLCMS/MS法等。结论抗风湿类中成药和保健品中非法添加化学药物的技术研究取得了一定进展。除了发展检测技术,从多方面加强监管也非常重要。To know about the advances on analytical technologies of illegally adulterated chemical substances in antirheumatic Chinese patent medicines and health foods.Researches on analytical technologies of illegally adulterated chemical substances in antirheumatic Chinese patent medicines and health foods were reviewed and analyzed.The results indicated that the adulterated chemical substances mainly included glucocorticoids,non-steroid anti-inflammatory drugs,analgesics and antibiotics.The analytical methods involved thin layer chromatography,high-performance liquid chromatography,high-performance liquid chromatography-mass spectrometry,and ultra performance liquid chromatography-mass spectrometry.Much progress has been made in analytical technologies of illegally adulterated chemical substances in antirheumatic Chinese patent medicines and health foods.In addition to the development of analytical technologies,it is also very important to strengthen the supervisions of illegally adulterated chemical substances.

关 键 词：中成药 保健品 非法添加 化学药物 检测技术 

分 类 号：R917[医药卫生—药物分析学]