神经外科无菌切口感染病原菌分布与危险因素分析  

Pathogenic bacteria distribution and risk factors related to aseptic surgical incision infection in neurosurgical patients

作　　者：谢朝云 熊芸 孙静 杨怀[2] 杨忠玲 XIE Zhao-yun;XIONG Yun;SUN Jing;YANG Huai;YANG Zhong-ling(Department of Nosocomical Infection Control,The Third Affiliated Hospital,Guizhou Medical University,Guiyang 550002,China;Department of Nosocomical Infection Control,Renmin Hospital of Guizhou Province,Guiyang 550002,China;Department of Clinical Laboratory,The Third Affiliated Hospital,Guizhou Medical University,Guiyang 550002,China)

机构地区：[1]贵州医科大学第三附属医院感染管理科,贵州都匀558000 [2]贵州省人民医院感染管理科,贵阳550002 [3]贵州医科大学第三附属医院检验科,贵州都匀558000

出　　处：《中国临床神经外科杂志》2018年第1期20-22,58,共4页Chinese Journal of Clinical Neurosurgery

基　　金：贵州省科技厅联合项目(黔科合LH字[2014]7162号);贵州省黔南州社会发展科技项目(黔南科合社字[2013]20号)

摘　　要：目的探讨神经外科无菌手术切口感染的病原菌与相关危险因素。方法回顾性分析2011年1月至2017年2月在我院神经外科行无菌切口手术治疗的8 478例病人临床资料。采用多因素Logistic回归分析检验手术切口感染危险因素。结果 8478例中,术后发生切口感染102例(1.20%)。多因素Logistic回归分析显示,血红蛋白浓度<90 g/L、美国麻醉师协会评级>Ⅱ级、切口长度≥10 cm、手术持续时间≥3 h、糖皮质激素增高、血清白蛋白浓度<30 g/L、急诊手术等是神经外科无菌手术切口感染的独立危险因素(P<0.05)。结论神经外科无菌手术切口感染与多种因素相关,临床应采取针对主要危险因素为主的综合措施,以降低神经外科无菌手术切口感染率。Objective To analyze the pathogens and risk factors related to aseptic surgical incision infection in the neurosurgical patients.Methods The clinical data of 8 478 neurosurgical patients undergoing aseptic operation in our hospital from January,2011 to February,2017 were analyzed retrospectively.The risk factors related to surgical incision infection were analyzed by multivariate Logistic regression analysis in these patients.Results Of 8 478 patients,102(1.20%)had surgical incision infection and 8 376 not.Multivariate Logistic regression analysis showed that the independent risk factors related to sterile surgical incision infection included hemoglobin concentration<90 g/L,ASA rating>Ⅱ,incision length≥10 cm and the duration of operation≥3 h,application of glucocorticoid,serum albumin concentration<30 g/L and emergency operation(P<0.05).Conclusion The aseptic surgical incision infection is related to many factors and comprehensive measures directed at the main risk factors should be clinically taken in order to reduce aseptic surgical incision infection rate in the neurosurgical patients.

关 键 词：神经外科 无菌手术 切口感染 危险因素 LOGISTIC回归分析 

分 类 号：R651.11[医药卫生—外科学]