7-羟基香豆素醛在检测次氯酸根中的应用  

Application of 7-hydroxylcoumarin-aldehyde in the detection of hypochlorite

作　　者：阴彩霞[1] 熊康明 霍方俊[2] YIN Caixia;XIONG Kangming;HUO Fangjun(Institute of Molecular Science,Shanxi University,Taiyuan 030006,China;Research Institute of Applied Chemistry,Shanxi University,Taiyuan 030006,China)

机构地区：[1]山西大学分子科学研究所,山西太原030006 [2]山西大学应用化学研究所,山西太原030006

出　　处：《河北大学学报（自然科学版）》2018年第1期28-32,共5页Journal of Hebei University(Natural Science Edition)

基　　金：国家自然科学基金资助项目(21672131;21775096;21705102);山西省人才支持计划资助项目(2014401);山西省归国基金资助(2017-026)

摘　　要：7-羟基香豆素醛在PBS(pH=7.4)的缓冲溶液中可以被用于检测次氯酸根.光谱实验结果表明,该探针在PBS(pH=7.4)的缓冲溶液中对次氯酸根的识别具有荧光增强的性质,并伴随着溶液的颜色由浅黄色变为深黄色,溶液的荧光由弱荧光变为深蓝色荧光.探针对次氯酸根的识别响应在1s内迅速完成,并且检测线可以达到51.75nmol/L.此外,7-羟基香豆素醛可以在HepG2细胞中对次氯酸根进行荧光成像.7-hydroxylcoumarin-aldehyde can be used to detect hypochlorite in PBS(pH=7.4)solution.The results of spectra show that the probe has a fluorescence enhancement property for hypochlorite recognition in PBS(pH=7.4)solution,and the color of the solution changes from light yellow to deep-yellow,and the fluorescence of the solution changes from weak fluorescence to deep-blue fluorescence.The recognition response of the probe to hypochlorite can be rapidly completed within 1s,and the detection limit is found to be as low as 51.75 nmol/L.In addition,the probe can be used for fluorescence imaging of hypochlorite in HepG2 cells.

关 键 词：7-羟基香豆素醛 次氯酸根 荧光增强 荧光成像 

分 类 号：O622.4[理学—有机化学]