磁共振弥散峰度成像对急性脑梗死分类的初步研究  

Preliminary research of the classification of the brain acute stroke by diffusion kurtosis imaging parameters

作　　者：陈芳 杨永贵[1] 刘欣 郭岗[1] CHEN Fang;YANG Yong-gui;LIU Xin;GUO Gang(Department of Radiology,the Second Hospital of Xiamen,Xiamen 361012,China)

机构地区：[1]厦门市第二医院放射影像科,厦门361012

出　　处：《磁共振成像》2018年第3期166-172,共7页Chinese Journal of Magnetic Resonance Imaging

基　　金：厦门市重要重大疾病联合攻关项目(编号:3502Z20149032);厦门市科技局科技计划项目(编号:3502Z20144050)~~

摘　　要：目的根据弥散峰度成像(diffusion kurtosis imaging,DKI)参数对急性脑梗死进行分类,初步探讨该分类在诊断及预后评估的价值。材料与方法选取46个急性脑梗死病灶,根据DKI参数MK、Ka及Kr的范围及信号差异将病灶分为Ⅰ类(MK、Ka及Kr均为高信号)、Ⅱ类(MK、Ka及Kr均为等低信号)、Ⅲ类(MK、Ka及Kr均为混杂信号)及Ⅳ类(MK、Ka及Kr范围或信号不一致)。四类病灶DKI参数进行单因素方差分析,每类病灶选取1个典型病例分析其预后。结果四类病灶的MK%、Ka%及Kr%有显著性差异(P<0.05),其他参数均无显著性差异。结合其他学者的研究成果及病例分析,提示Ⅰ类病灶预后可能较差,Ⅱ类及Ⅲ类病灶预后可能较好。结论从某种程度上,根据DKI参数对急性脑梗死分类在病灶的诊断、治疗方案选择及预后评估有一定的临床价值。Objective:To classify the acute stroke lesions according to the diffusion kurtosis imaging(DKI)parameters and discuss the significance of the classification in diagnosis and prognosis.Materials and Methods:We chose 46 acute stroke lesions in brain and divided into 4 types.MK,Ka and Kr show hyper-intensity in TypeⅠ.MK,Ka and Kr show isointensity or hypo-intensity in TypeⅡ.MK,Ka and Kr show mixed signal intensity in TypeⅢ.The ranges or intensity of MK,Ka and Kr are diverse in Type IV.The difference of DKI parameters between four types was accessed by one-way analysis of variance.We chose one case of each type to analyze the prognosis.Results:It shows that MK%,Ka%and Kr%of four types have a significant difference.Other parameters have no significant difference.TypeⅠmay indicate the bad prognosis.TypeⅡand TypeⅢmay indicate better prognosis,the volume of lesions may decrease.Conclusions:To some degree,the classification of acute stroke lesion by DKI parameters has significance in diagnosis,treatment and prognosis.

关 键 词：弥散峰度成像 急性脑梗死 分类 弥散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.33[医药卫生—诊断学]