2013年至2015年昆明地区普通人群HCV感染状况分析  

An Analysis of the Status of General Population with HCV Infection in Kunming Region from 2013 to 2015

作　　者：丁家伟[1,2] 徐益恒 李劲榆[1,2] 高凌 吴翰欣[1,2] 温艳萍 李梦仙[1,2] 邰文琳 DING Jia-wei;XU Yi-heng;LI Jin-yu;GAO Ling;WU Han-xin;WEN Yan-ping;LI Meng-xian;TAI Wen-lin(Dept.of Clinical Laboratory,The 2nd Affiliated Hospital of Kunming Medical University;Yunnan Research Center of Molecular Diagnostics,Kunming Yunnan 650101,China)

机构地区：[1]昆明医科大学第二附属医院检验科 [2]云南省分子诊断研究中心,云南昆明650101

出　　处：《昆明医科大学学报》2018年第2期88-93,共6页Journal of Kunming Medical University

基　　金：云南省医疗卫生单位内设研究机构基金资助项目(2014NS114)

摘　　要：目的云南吸毒人群丙型肝炎病毒(HCV)感染率高,对普通人群HCV感染的防控工作面临严峻挑战.旨在研究分析昆明地区HCV感染人群流行病学特征,为昆明地区HCV感染制定防控措施和开展科学防控干预提供一定的参考信息.方法采用回顾性方法对2013年至2015年来昆明医科大学第二附属医院接受血清HCV-Ig G抗体检测的受检者160 239例进行血清流行病学的统计学分析.结果 2013年至2015年昆明地区普通人群HCV感染率分别为1.11%、1.04%和0.91%;男性明显高于女性(男性1.30%vs.女性0.91%,P<0.05);31~60岁中老年人高于其它年龄.结论男性和31~60岁中老年人为2013年至2015年昆明地区HCV感染的高发人群,这种流行病学特征可为昆明地区开展对HCV感染及其导致肝硬化、肝功能衰竭和肝细胞癌的防控工作,制定科学的策略和干预措施提供一定的参考和依据.Objective The aimof this study was to analyze the HCV seroprevalence in the general population visiting the Second Affiliated Hospital of Kunming Medical University.Methods Between January 2013 and December 2015,a total of 160,239 subjects were screened for the presence of anti-HCV antibodies in blood serum.Anti-HCV antibodies in serum samples were detected by enzyme-linked immunosorbent assay(ELISA).The results of anti-HCV were analyzed in the features of year,sex and age.Results The HCV seroprevalence in the general population from 2013 to 2015 was 1.11%,1.04%and 0.91%,respectively,which was significantly higher in men than in women(1.30%vs.0.91%,<0.05).The highest HCV seroprevalence occurred in aged 31-65 years.Conclusions The analysis of the data suggests that the features of HCV-positive including year,sex and age could be beneficial for formulating scientific strategy and intervention measures of HCV infection and liver cirrhosis,liver failure and hepatocellular carcinoma caused by HCV in Kunming.

关 键 词：丙型肝炎病毒 丙型肝炎病毒抗体 普通人群 感染率 血清流行病学 

分 类 号：R512.63[医药卫生—内科学]