65例脓毒性休克患者血浆降钙素原及C反应蛋白水平的临床分析  

Clinical analysis of plasma procalcitonin and C-reactive protein levels in 65 patients with septic shock

作　　者：孟祥忠 卫峰 王娜 史振华 丁东瑞 MENG Xiangzhong;WEI Feng;WANG Na;SHI Zhenhua;DING Dongrui(ICU,The 254 th Hospital of People′s Liberation Army,Tianjin,300142)

机构地区：[1]解放军第二五四医院重症医学科,天津300142

出　　处：《实用临床医药杂志》2018年第3期120-122,共3页Journal of Clinical Medicine in Practice

基　　金：天津市卫生局科研基金项目(TW-2013B-224)

摘　　要：目的分析65例脓毒性休克患者血浆降钙素(PCT)原及C反应蛋白(CRP)水平。方法选择本院ICU严重感染患者65例脓毒性休克患者(脓毒性休克组),治疗后死亡12例(死亡组),存活53例(存活组)。同时期选择本院接收的63例非脓毒性休克患者(对照组)。对比分析脓毒性休克组患者及对照组在治疗前及治疗后3、6、12 d的PCT、CRP水平。结果治疗前,脓毒性休克组患者PCT、CRP水平均明显高于对照组(P<0.05);接受治疗后3、6、12 d,脓毒性休克组及PCT、CRP水平均高于对照组,差异有统计学意义(P<0.05);死亡组在治疗后3、6、12 d,PCT、CRP水平均高于存活组,差异有统计学意义(P<0.05)。结论 PCT、CRP水平对于脓毒性休克患者病情发展程度具有重要的判定价值。Objective To analyze the levels of plasma procalcitonin(PCT)and C-reactive protein(CRP)in 65 patients with septic shock.Methods A total of 65 severe sepsis patients(septic shock group)were selected in our hospital in ICU.After treatment,12 patients died(death group),and 53 cases survived(survival group).At the same time,63 patients with non septic shock were selected(control group).The PCT and CRP levels of the septic shock group and control group were compared and analyzed before and at 3,6 and 12 d after treatment.Results Before treatment,PCT,CRP levels in septic shock group were significantly higher than that in the control group(P<0.05).At 3,6,12 d of treatment,septic shock group was higher than the control group,the death group was higher than the survival group(P<0.05).Conclusion The levels of PCT and CRP are important in diagnosis of septic shock progress.

关 键 词：血浆降钙素原 脓毒性休克 C反应蛋白 

分 类 号：R631[医药卫生—外科学]