腹腔内化疗联合全身热疗治疗恶性腹腔积液的临床研究  

Clinical study of intraperitoneal chemotherapy combined with whole body thermal therapy in the treatment of malignant seroperitoneum

作　　者：王革芳 吴成利 姜程远 虞喜豪[1] 王蕾 朱琴 WANG Gefang;WU Chengli;JIANG Chengyuan;YU Xihao;WANG Lei;ZHU Qin(Department of Oncology,The 85 th Hospital of people′s liberation Army,Shanghai,200052)

机构地区：[1]中国人民解放军第八五医院肿瘤科,上海200052

出　　处：《实用临床医药杂志》2018年第3期123-124,127,共3页Journal of Clinical Medicine in Practice

摘　　要：目的研究腹腔化疗联合全身热疗对恶性腹腔积液的近期疗效及毒副作用。方法将60例恶性肿瘤患者随机分为2组,对照组30例接受单纯腹腔内化疗,排空腹水后注入化疗药物,研究组30例接受腹腔化疗联合全身热疗。评价2组患者的近期疗效及毒副反应。结果研究组生活质量改善有效率为90%,高于对照组的60%(P<0.05)。2组毒副反应差异无统计学意义(P>0.05)。结论腹腔内化疗联合全身热疗治疗恶性腹腔积液较单纯腹腔内化疗疗效、耐受性好。Objective To study the short-term efficacy and toxicity of intraperitoneal chemotherapy combined with thermotherapy in the treatment of malignant ascites.Methods A total of 60 patients were randomly divided into control group(30 cases)and study group(30 cases).The control group received intraperitoneal chemotherapy and was given chemotherapy drugs injecting after drainage of ascites,while the study group was given intraperitoneal chemotherapy combined with whole body thermal therapy.The short-term efficacy and toxicity were evaluated.Results The efficacy rate of life quality improvement in the study group was higher than that in the control group(90%vs.60%,P<0.05).There was no significant difference between the two groups in toxicity(P>0.05).Conclusion Intraperitoneal chemotherapy combined with whole body thermal therapy in the treatment of malignant ascites has higher efficacy and tolerance than intraperitoneal chemotherapy alone.

关 键 词：恶性腹腔积液 全身热疗 腹腔内化疗 

分 类 号：R453[医药卫生—治疗学]