P(4-VPPS-co-DMAPS)两性离子共聚物膜的制备及表征  

Preparation and Characterization of Zwitterionic Copolymer P(4-VPPS-co-DMAPS)Membrane

作　　者：孙云龙[1] 陈昌林 雷昆 许冠哲 徐衡 郎美东[1] SUN Yun-long;CHEN Chang-lin;LEI Kun;XU Guan-zhe;XU Heng;LANG Mei-dong(School of Materials Science and Engineering,East China University of Science and Technology, Shanghai 200237,China;School of Chemistry and Chemical Engineering,Shanghai Jiao Tong University,Shanghai 200240,Chin;Collaborative Innovation Center for Petrochemical New Materials,Anqing 246011,Anhui,China)

机构地区：[1]华东理工大学材料科学与工程学院,上海200237 [2]上海交通大学化学化工学院,上海200240 [3]石油化工新材料协同创新中心,安徽安庆246011

出　　处：《功能高分子学报》2018年第2期181-188,共8页Journal of Functional Polymers

摘　　要：首先,以4-乙烯基吡啶(4-VP)与甲基丙烯酸二甲氨乙酯(DMAEMA)为单体通过自由基共聚,得到聚(4-乙烯基吡啶-co-甲基丙烯酸二甲氨乙酯)共聚物(P(4-VP-co-DMAEMA));然后,用1,3-丙磺酸内酯对P(4-VP-co-DMAEMA)侧链进行季铵化改性,得到不同离子化修饰程度的P(4-VP-co-DMAEMA)的两性离子共聚物(P(4-VPPS-co-DMAPS))。采用傅里叶转换红外光谱(FT-IR)、核磁共振氢谱(~1 H-NMR)和凝胶渗透色谱(GPC)对P(4-VP-co-DMAEMA)和P(4-VPPS-co-DMAPS)的化学结构进行表征。用万能拉力试验机、差示扫描量热分析仪(DSC)、热重分析仪(TG)以及稀释涂布平板法对P(4-VP-co-DMAEMA)和P(4-VPPS-co-DMAPS)薄膜的力学性能、热学性能以及抗菌/防污性能进行了表征。探究了单体单元物质的量之比、季铵化修饰程度对P(4-VPPS-co-DMAPS)薄膜材料物理化学性能以及功能性的影响。结果表明:当两种单体单元的物质的量之比(n_(4-VP/nDMAEMA))为3/7,离子化修饰程度为20%时,得到的两性离子共聚物薄膜具有一定的热稳定性、韧性和强度,且兼具优异的抗菌/防污特性。Zwitterionic copolymers are generally considered to be applied in nonfouling applications to prevent nonspecific protein adsorption as well as to minimize bacterial or mammalian cell adhesion and the research takes advantage of zwitterionic copolymers in film materials.Firstly,4-vinyl pyridine(4-VP)reacted with 2-(dimethylamino)ethyl methacrylate(DMAEMA)by radical copolymerization to prepare P(4-VP-co-DMAEMA)with different copolymerization ratios.Then,the quaternary amination modification of P(4-VP-co-DMAEMA)was implemented by different amounts of 1,3-propanesultone to obtain functional zwitterionic copolymer P(4-VPPS-co-DMAPS)with different ionization degrees.The chemical structures of P(4-VP-co-DMAEMA)and P(4-VPPS-co-DMAPS)were characterized and analyzed by Fourier Transform Infrared Spectrum(FT-IR),Nuclear Magnetic Resonance Hydrogen(1H-NMR)and Gel Permeation Chromatography(GPC).The mechanical property,thermal property and antibacterial/antifouling performances of P(4-VP-co-DMAEMA)and P(4-VPPS-co-DMAPS)were tested and analyzed by universal tensile testing machine,Differential Scanning Calorimetry(DSC),Thermogravimetric Analysis(TG),dilution coated plate method and optical microscope.Effects of molar quantity ratio of monomer unit and ionization degree of zwitterionic copolymer P(4-VPPS-co-DMAPS)on the physical,chemical performances and functionalities of P(4-VPPS-co-DMAPS)were also studied.When the real molar ratio(n 4-VP/n DMAEMA)in P(4-VP-co-DMAEMA)was about 1,the elongation at break was about 350%and breaking strength was 6 MPa,which was applicable to film materials.Although the high ionization degrees was helpful to antibacterial and antifouling ability of P(4-VPPS-co-DMAPS).If the ionization degree of P(4-VPPS-co-DMAPS)was high,the film was easy to absorb water,which led to bad mechanical property and limited their application.It was important to balance antibacterial,antifouling ability with good mechanical property of P(4-VPPS-co-DMAPS).The results showed that the best film(P(4-VPPS-co-DMAPS)-2/20%),exh

关 键 词：两性离子共聚物 共聚物膜 功能化 抗菌性 防污性 

分 类 号：TQ95[化学工程]